Adverse events frequently occur with chemotherapy, radiation therapy involving the oral cavity, and hematopoietic stem cell transplantation in cancer treatment. The Multinational Association of Supportive Care in Cancer and the International Society for Oral Oncology （MASCC/ISOO） have developed a systematic review methodology and published a updated version of the “MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy” in 2019-2020. In addition, an official Japanese translation of the summary overview was also published. However, because it is an international guideline, some references are made to unapproved drugs or off-label use in Japan. In addition, some parts of the summary outline do not convey the intent derived from the original text. This paper introduces the contents of the revised guideline and details the contents of the summary overview of the guideline with the above-mentioned problems in mind.

View full abstract

Pleomorphic adenoma is the most common tumor arising in salivary glands. It frequently develops in the parotid and palatine glands, but extremely rarely in the sublingual gland. We report on a 44-years-old woman with pleomorphic adenoma of the sublingual gland. Her chief complaint was a painless mass in the right side of the oral floor. Since the diagnosis of pleomorphic adenoma was obtained by the biopsy, the extirpative surgery of the tumor including the sublingual gland was carried out. There has been no sign of recurrence for 2 years after the surgery.

View full abstract