Objective: We examined the usefulness of nutritional therapy in autologous stem cell transplantation (auto-PBSCT).
Method: We investigated 25 patients who received auto-PBSCT in our hospital from 2006 to 2010 in terms of quantity of nutritional supply.
Result: Weight, skeletal muscle mass, and fat mass during the nutritional intervention period did not show any significant differences (Student’ st-test). A deviation in %LBW (loss of body weight) over the course of 3 months (%LBW ≧ 7.5%) was seen in 3 of 25 cases during the intervention period. Associations were evident between weight and c hange in skeletal muscle mass (linear regression analysis: r=0.77, p<0.001), supply heat capacity (r=0.41,p<0.05), and skeletal muscle change and protein supply (r=0.40, p<0.05) during the nutritional intervention period. The 22 cases without %LBW deviation (mean, 2.4±1.7%) were 26 ± 5 kcal/kg (IBW: ideal body weight) /day, protein 0.9 ± 0.2 g/kg (IBW) /day.
Discussion: Decreases in skeletal muscle advance with weight loss in auto-PBSCT. Nutritional therapy in consideration of adverse events is useful to maintain quality of life.
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