Purpose: Sarcopenia has recently been attracting attention as an early sign of the need for nursing care in older adults. Some studies have reported that oral health is related to sarcopenia and its diagnostic factors (hand grip strength, walking speed, and skeletal muscle mass). However, the relationship between oral health and sarcopenia remains poorly investigated and no review to date has compiled the available research on this relationship. The aim of this review was to summarize the current evidence describing the association between oral health and sarcopenia.
Study selection: The internet database PubMed was searched using various combinations of related and synonymous keywords for “oral” or “dental” or “oral health” or “oral function” and “sarcopenia” or “walking speed” or “hand grip strength” or “skeletal muscle mass.” A total of 27 studies found to be eligible were critically evaluated and their key findings were summarized.
Results: Most of the studies were cross-sectional and conducted in Japan. A wide range of oral factors, including number of teeth, occlusal support, periodontal state, occlusal force, mastication, tongue pressure, and swallowing, were covered. The overall findings were that oral health indices could be significantly associated with sarcopenia and its diagnostic factors.
Conclusions: Relationships may exist between aspects of oral health and sarcopenia or its diagnostic factors. However, reports showing associations between oral health and sarcopenia are scarce, and definitive conclusions could not be drawn. Further longitudinal studies are necessary to confirm these relationships.

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Purpose: A bioactive high performance polymer (BioHPP) and computer-aided design/computer-aided manufacturing (CAD/CAM) composite resin materials are a relatively new class of dental biomaterials, that are biocompatible and have good aesthetic features. In this review paper, we will summarize literature and publication data on the characteristics of the mentioned materials, as well as their potential application in the dental prosthetics.
Study selection: Available studies and literature reviews from PubMed, SCIndex, Scopus and Google Scholar corresponding to polyetheretherketone (PEEK), high-performance polymers, reinforced composite materials, composite materials, resins, glass-fiber reinforced materials, CAD/CAM materials, dental implants, removable and fixed dental were reviewed.
Results: To avoid many disadvantages of metals and their alloys in dental practice, such as inadequate color, high density, thermal conductivity and possible allergic reactions, materials based on polymers (such as BioHPP), and CAD/CAM composite resins are being developed. These materials have significantly better aesthetics and physical-mechanical properties. They are biocompatible materials that are lightweight, resistant, durable, exhibit high bending and compression resistance.
Conclusions: The use of CAD/CAM composite resin materials and BioHPP in dentistry has begun recently, so the data about their potential clinical use are limited. Most of their features have been demonstrated through laboratory testing, while clinical studies are relatively scarce, so the need for further clinical trials is emphasized.

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Purpose: The primary purpose of this study was to examine the clinical performance of monolithic zirconia single crowns in terms of short-term failure or complications. The secondary purpose was to detect the originating flaws of clinically failed monolithic zirconia crowns to find the causes of failure.
Methods: A short-term prospective cohort study based on record evaluation and clinical examination of patients treated with tooth-supported monolithic zirconia crowns was performed in the Department of Fixed Prosthodontics, Tohoku University Hospital, Japan. The crowns were prepared during the follow-up period from April 2014 to July 2018. The 3.5-year cumulative success and survival rates were set as primary endpoints. Fractures of the crown or fragments were inspected under a scanning electron microscope for descriptive fractography.
Results: During the study period, 40 monolithic zirconia crowns were placed. Four crowns experienced clinical complications, including: 1) fracture of the crown (two crowns), 2) abrasion of the crown (one crown), and 3) fracture of the antagonist tooth (one crown). The estimated Kaplan-Meier 3.5-year success and survival rates were 90.5% (95% confi dence interval [CI]: 73.1–97.1) and 92.8% (95% CI: 74.1–98.3), respectively. Fractography revealed that all fractures were initiated from the wear phase on the occlusal surface.
Conclusions: The results of this study suggest that the molar application of monolithic zirconia crowns requires detailed attention to interocclusal clearance and the restoration of the antagonist tooth.

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Purpose: Poly(methyl methacrylate) (PMMA) is the most commonly used material in the production of dental prostheses, and its application is often accompanied by the formation of biofilm. The aim of this work was the preparation of a PMMA/gold nanoparticles (AuNps) composite to improve the antimicrobial properties of heat-polymerised PMMA. The AuNPs were synthesised from gold (III) acetate by Ultrasonic Spray Pyrolysis (USP).In the present study, flexural strength and elastic modulus were investigated, as well as thermal conductivity, density and hardness of the PMMA/AuNps` nanocomposite, with different concentrations of AuNps. Flexural strength and elastic modulus were measured using a three-point bending test, and surface hardness was evaluated using the Vickers hardness test. The thermal conductivity of the samples was measured using the Transient Plane Source (TPS) technique. Density was determined by the pycnometry procedure. Statistical analysis was conducted on the data obtained from the experiments.
Results: The flexural strength and elastic modulus of AuNps/PMMA nanocomposites decreased for all groups containing AuNps. Thermal conductivity and density increased in all groups containing AuNps compared to the control group, but it was not significant in all groups. Vickers hardness values increased significantly with an increase in AuNps` content, with the highest value 21.45 HV obtained at 0.74 wt% of AuNps. Statistical analysis was performed by means of the SPSS 19 software package.
Conclusions: Incorporation of AuNps into heat-polymerised PMMA resin led to decrease of the flexural strength and elastic modulus. At the same time, the density, thermal conductivity and hardness increased.

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Purpose: This study evaluated the influence of different surface treatments of zirconia used to enhance bonding with veneering porcelain, and thermocycling on the resistance to porcelain cracking and delamination during fatigue test.
Methods: Bilayer ceramic discs were made from zirconia blocks (IPS e.max Zircad MO, Ivoclar Vivadent – 0.7 mm thickness) and randomized into 8 groups (n= 15) according to two factors: ‘zirconia surface treatment’ (Control; Grinding – diamond bur; Air-abrasion – aluminum oxide particles; and Liner – application of a ceramic liner [IPS e.max Zirliner, Ivoclar Vivadent]); and ‘thermocycling’ (presence – 12,000 thermal cycles; 5-55ºC; or absence). The discs were veneered with porcelain (IPS e.max Ceram, Ivoclar Vivadent – 0.7 mm; totaling 1.4 mm thickness) according to ISO 6872:2015 for biaxial flexure strength testing. Fatigue tests (step-stress approach; 20 to 100 MPa; step of 10 MPa; 10,000 cycles per step; 10 Hz frequency) were run, followed by the data analysis (Kaplan-Meier and Mantel-Cox post-hoc tests). Analysis of roughness, topography, crystallographic phase arranges and fractography were also executed.
Results: The surface treatment and thermocycling did not influence the porcelain crack nor delamination resistance. When only comparing the surface treatments for crack resistance outcome, the liner application depicted the worst fatigue performance in comparison to grinding and air-abrasion, while all groups were similar for delamination.
Conclusions: Neither the surface treatment of the zirconia nor the thermocycling influences the porcelain crack resistance or the resistance to delamination of the bilayer porcelain-veneered zirconia specimens.

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Purpose: To evaluate the influence of resin cement type, surface pretreatment and autoclave sterilization on the retention of Y-TZP crowns to Ti-base abutments.
Methods: Y-TZP crowns were designed and milled to fit Ti-base abutments. Crowns were cemented using either a conventional resin cement (conventional) with a universal adhesive or a self-adhesive resin cement (self-adhesive), both following no surface pretreatment (No) or Ti-base abutment sandblasting (SB) (n=20/group). Half of the cemented samples were subjected to in-office autoclave sterilization. Pullout testing was performed in a universal testing machine at a speed of 1 mm/min until crown displacement. Data were statistically evaluated through a linear mixed model following post hoc comparisons by LSD test.
Results: Pullout data as a function of cement type demonstrated higher retention for conventional relative to self-adhesive cement (p < 0.001). Ti-base sandblasting (SB) favored crown retentiveness over No pretreatment (p < 0.001). Sterilized crowns exhibited higher pullout values than non-sterile (p=0.036). All the two- and three-factor interaction analyses corroborated with the superior adhesive strength of conventional compared to self-adhesive cement (all, p < 0.011), as well as, SB relative to No pretreatment (all, p < 0.024). While autoclave sterilization maximized bond strength when self-adhesive cement (data collapsed over surface pretreatment, p < 0.050) and No pretreatment were evaluated (data collapsed over surface pretreatment, p < 0.013), no significant difference was observed for conventional resin cement (p=0.280) and SB (p=0.878) groups.
Conclusions: Conventional resin cement and/or Ti-base sandblasting increased Y-TZP crown retentiveness, with no significant influence of autoclave sterilization. Autoclaving increased retentiveness when self-adhesive cement and/or no Ti-base pretreatment were used.

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Purpose: Polymers are used in dentistry on a daily basis due to their mechanical, functional and aesthetic properties. However, such biomaterials are subject to deterioration in the oral environment. Thus, this study aimed to evaluate the structural properties of five commonly used dental polymers to determine their best clinical indications.
Methods: Four hundred-fifty samples of five dental polymers (polyethylenterephthalat - glycol modified (PG), polymethyl methacrylate (PA), ethylene vinyl acetate(E), polycarbonate (PC), polyetheretherketone (PK) were prepared to investigate their thermal, structural and chemical characteristics using energy dispersive spectroscopy (EDS), Fourier transform infrared analysis(FTIR), scanning electron microscopy (SEM), differential scanning calorimetry(DSC), thermogravimetric analysis(TGA), X-ray diffraction(XRD), and Shore D hardness test. Data were analyzed using one-way ANOVA, Tukey’s HSD, and Levene’s tests (α=0.05).
Results: PK (87.2) and PA (82.4) displayed the highest hardness values and smooth surfaces, as observed with SEM (p<0.001). Silica was detected in PK, PA, and E by EDS and XRD. The highest glass transition temperature was recorded for PC (145.00±2.00°C) and PK (143.00±1.87°C), while the lowest value was measured for E (50.00±2.12°C)(p<0.001).The highest mass loss was detected for PG (91.40±1.40%) by TGA.
Conclusions: PA and PK polymers can be used for stress-containing treatments due to their mechanical properties. These two materials are also advantageous in terms of plaque accumulation as these polymers reveal smoother surfaces than other groups. Insufficient physical and thermal properties require the use of E with caution and only in limited clinical indications.

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Purpose: The aim of this study was to compare and contrast the diagnostic accuracy of multiple online symptom checkers when used for the diagnosis of orofacial pain and oral medicine related disease vignettes. The comparison condition used in this study was the diagnostic accuracy achieved by advanced specialty residents on these same vignettes using a virtual patient system.
Methods: 27 individual disease vignettes were utilized. These vignettes had a variety of orofacial pain and oral medicine diseases. Post graduate orofacial pain and oral medicine residents at our University of Southern California interacted with their randomly assigned virtual patients were analyzed [n=574]. Virtual patient accuracy was based on whether the user selected the primary diagnosis as one of their top four choices after interviewing. Eleven English-language symptom checkers accuracy was based on whether the vignettes produced the primary diagnosis as one of their top four choices. Using these data, symptom checker and virtual patient accuracy rates were calculated.
Results: The primary diagnosis on virtual patient encounters was found within the top four choices a mean of 67.2% of the time. The primary diagnosis for the same vignettes entered into the 11 symptom checkers was found within the top four choices a mean of 5.9% of the time.
Conclusions: The accuracy of currently available symptom checkers that patient might use for self-diagnosis of common orofacial pain and oral medicine diseases was low, this result suggest that the improved diagnostic algorithms are needed.

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Purpose: To evaluate the clinical outcomes of minimally invasive ceramic restorations executed by dentists with different levels of experience.
Methods: Sixteen professionals were divided into 4 groups according to their experience levels. These included G1: up to 2 years since graduation, G2: 2-5 years, G3: 5-10 years, and G4: more than 10 years. All professionals were trained to follow the same standardized clinical protocol, but were unaware of the research objectives. A single evaluator followed the clinical treatments and recorded the complications and errors that occurred during the execution of the protocol. Ninety-one full crowns, 137 veneers, and 46 no-preparation veneers were prepared from lithium disilicate. Follow-ups were performed immediately and at 30, 180, and 360 days after the cementation and the evaluation based on the modified United States Public Health Service criteria. Ceramic chipping/fracture and debonding were considered failures. Fractures were replicated and submitted to fractographic analysis.
Results: The highest number of failures were found in G1 followed by G3 and the lowest number of failures were found in G2. The level of success was 94% after 360 days. The fractographic analysis demonstrated the external surface of restorations as the critical area and suggested that failures might occur due to noncompliance with the clinical protocol. There was no correlation between professional experience and number of failures or patient satisfaction.
Conclusions: Professional experience was not a decisive for patient satisfaction and success of minimally invasive ceramic restorations, and noncompliance with the clinical protocol was associated with early ceramic restoration failures.

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Purpose: This study investigated the relationship between peri-implant tissue health and the presence of keratinized mucosa (≥ 2 mm) using multivariate analysis.
Methods: A total of 334 dental implants placed in 111 partially edentulous patients (34 males, 77 females) and restored with fixed prostheses were included in this study. The patients were recalled 12–146 months after completion of the prosthodontic treatment. Clinical parameters included modified plaque index (mPI), modified bleeding index (mBI), probing pocket depth (PPD), and radiographic bone loss (BL). The effects of the following potential explanatory variables on these parameters were analyzed: the presence of keratinized mucosa, age, sex, oral hygiene status, history of periodontitis, cigarette smoking, implant site, and time elapsed since prosthesis delivery. Statistical analysis included multivariate ordinal logistic regression and generalized estimating equations. Significance wa s established when two-sided p-values were less than 0.05.
Results: The mPI, mBI, and PPD in the presence or absence of keratinized mucosa did not show statistically significant differences. However, the presence of keratinized mucosa was significantly related to BL (odds ratio 4.33, p < 0.01).
Conclusions: The results of our study suggest that the presence of keratinized mucosa is useful for reducing bone resorption and can help to maintain peri-implant tissue health

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Purpose: To evaluate the influence of quantity and positioning of veneered zirconia specimens during firing of porcelain on their fatigue performance and colorimetric differences.
Methods: Bilayer discs (Ø=15 mm) were made, following ISO 6872 guidelines, using a Y-TZP core (yttria-stabilized tetragonal zirconia polycrystal ceramic; VITA In-Ceram YZ) and a feldspathic veneering material (VITA VM9), being both layers with 0.7 mm thickness. Y-TZP discs were sintered, the veneering material was applied over it, and the bilayer specimens were fired according to two factors (n=20): ‘quantity’ (1 or 5 samples per firing cycle; G1 and G5 groups respectively) and ‘positioning’ of the specimens inside the furnace (center or periphery of the refractory tray; G5C and G5P groups, respectively). The CIEL*a*b* parameters were recorded with a spectrophotometer and the color difference (ΔE 00 ) and translucency (TP 00 ) were calculated using CIEDE2000 equations. The step-stress fatigue test was performed with the veneer facing down (region of tensile stress concentration), 10 Hz frequency, initial tension of 20 MPa for 5,000 cycles, followed by steps of 10,000 cycles using a step size of 10 MPa, up to 100 MPa; data from strength and number of cycles for failure were recorded for statistical analysis.
Results: Unacceptable color differences (ΔE 00 >1.8) were observed comparing G5C vs. G1 (quantity) and G5C vs. G5P (positioning), meanwhile translucency parameters were not affected. Besides, only the ‘quantity’ factor influenced the fatigue performance (G1>G5C). None of the tested specimens survived beyond 90N and/or 75000 cycles.
Conclusions: The quantity and position of the specimens during firing influence the final color of porcelain-veneered zirconia, and firing one specimen per cycle improved the fatigue performance of the bilayer system.

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Purpose: This study investigated the in-vitro performance of anterior implant-supported fixed dental prostheses (FDP). The effect of ceramics, fabrication, finalization and the presence of a screw-channel wa s investigated.
Methods: Identical anterior ceramic FDPs (tooth 11-13; n=80) were milled (Lithiumdisilicate (LiSiCAD, emaxCAD, Ivoclar-Vivadent), Lithiumaluminiumsilicate (LiAlSi, experimental material) or pressed (Lithiumdisilicate (LiSiPress, emaxPress, Ivoclar-Vivadent), Lithiumsilicate (ZLS, CeltraPress, Dentsply Sirona). FDP-groups (n=8 per material and group) simulated a cemented or screw-retained approach. After cementation or screwing on titanium abutments, thermal cycling and mechanical loading (TCML) was performed on all restorations to mimic 5-year clinical performance. Performance and fracture force were determined and failures were analyzed. Statistics: (Kolmogorov-Smirnov-test, one-way-ANOVA; post-hoc-Bonferroni, multivariate-regression, α=0.05).
Results: All FDPs survived TCML without aging, cracks, fractures or chipping. For FDPs without screw channel fracture values varied between with 839.8±112.3N (LiAlSi glazed) and 1485.9±232.6N (LiSiCAD). With screw channel, fracture results varied between 701.4±220.1N (LiALSi glazed) and 1516.3±253.7N (LiSipress). The type of material had a significant influence on the fracture results (LiSi>ZLS>LiAlSi; p≤0.012). Fabrication and finalization had no influence on the results. A screw channel did not significantly (p≥0.135) reduce the fracture force of the FDPs. Type of failure was mostly characterized by a fracture of the connector (LiSi, LiAlSi) or the abutment (ZLS, LiAlSi).
Conclusions: FDPs survived TCML without failures indicating that the in vitro performance was not influenced by the tested parameters. Composition of ceramic material has significant influence on the fracture resistance of implant supported LiSi based FDPs. Screw channel, fabrication or finalization did not weaken the FDPs.

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Purpose: The purpose of this study was to investigate the accuracy of removable partial denture frameworks fabricated by 3D-printed pattern casting (AM-Cast) and selective laser sintering (SLS) under different co nditions with a reinforcement bar.
Methods: A partially edentulous model was scanned with a dental laboratory scanner, and CAD software was used to design the framework. Reinforcement bars (n=0-2) were set on the lingual side of the framework. 3D scanning of the fabricated frameworks by AM-Cast and SLS was performed, and the obtained data were overlapped with the design data. The differences in shape among setting conditions of the bar were statistically compared using the Bonferroni method after the Kruskal–Wallis test.
Results: The ranges in differences of the AM-Cast-0, AM-Cast-1, and AM-Cast-2 were -0.167 to 0.128 mm, -0.101 to 0.105 mm, and -0.185 to 0.015 mm, respectively. The ranges of SLS-0, SLS-1, and SLS-2 were -0.166 to 0.035 mm, -0.182 to 0.049 mm, and -0.138 to 0.038 mm, respectively. Large discrepancies were observed at the joining area of the lingual bar on the right side of the AM-Cast. A significant difference was found between the AM-Cast-0 and AM-Cast-1, and between the AM-Cast-0 and AM-Cast-2.
Conclusions: The setting conditions of the reinforcement bar affected the accuracy of the lingual bar in the AM-Cast; however, no effect was observed on the displacement of the central area of the lingual bar in SLS. Setting a single reinforcing bar on the retentive latticework contributed to improving the accuracy of the lingual bar in the AM-Cast but not the displacement of the central area of the lingual bar in SLS.

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Purpose: In this study, we aimed to investigate the effect of glucose metabolism on bone healing after tooth extraction in an osteoporosis rat model administered zoledronic acid (ZA) and dexamethasone (DX).
Methods: In total, 24 male Wistar rats (4 weeks old) were randomly assigned to four groups: Control (subcutaneous physiological saline), ZD (subcutaneous ZA and DX twice a week), Ins+ZD (subcutaneous insulin followed by ZD treatment), and Met+ZD (oral metformin followed by ZD treatment). Blood was collected every two weeks . Two weeks after treatment initiation, the first molar tooth on the right maxilla was extracted from all rats. Four weeks later, the rats were sacrificed, and bone healing was assessed. Maxillae samples were fixed and scanned using micro-computed tomography for quantifying areas of bone defects. Hematoxylin-eosin and tartrate-resistant acid phosphatase (TRAP) staining were performed to evaluate bone apoptosis and osteoclast number.
Results: In all experimental groups, body weight was statistically lower than that in the Control group, with no changes observed in uncarboxylated osteocalcin concentrations. The radiological analysis revealed that insulin or metformin administration improved healing in the tooth extraction socket (p < 0.01). Histological examination revealed that the osteonecrosis area was reduced in the Ins+ZD and Met+ZD groups (p < 0.01). TRAP staining presented increased osteoclast numbers in the ZD group when compared with that observed in the Control.
Conclusions: Tooth extraction with long-term ZA and DX administration inhibited bone remodeling and induced bisphosphonate-related osteonecrosis of the jaw-like lesions. Metformin exerted protective effects ag ainst osteonecrosis of the jaw.

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Purpose: To evaluate the effect of Er:YAG laser on the roughness, surface topography, and bond strength to resin luting cement based on chemical and micro-abrasion pretreatments of different computer-aided design/computer-aided manufacturing materials.
Methods: A polymer-infiltrated-ceramic-network (PICN) material (Vita Enamic, VE), three indirect resin composite (Cerasmart, CS; Shofu HC, SH; Lava Ultimate, LU), and one lithium disilicate ceramic (IPS e.max CAD, EM) blocks were subjected to one of the following pretreatments: no treatment (NC ), Er:YAG etching with one of two powers (either 3 or 6 W), hydrofluoric acid (HF) etching, self-etching ceramic primer (ME), or micro-abrasion (MA). The shear bond strength (SBS) of resin luting cement to pretreated materials was tested. Surface roughness was measured via atomic force microscopy, and surface topography was analyzed via scanning electron microscopy. Two-way analysis of variance, Tukey post-hoc test, and Pearson correlation were applied.
Results: Etching EM and VE with HF or the ME resulted in the highest SBS values in their groups (P < 0.05). LU, SH, VE, and CS indicated similar SBS values when treated with 3 W, 6 W, and MA. The highest surface roughness (Sa ) values were obtained for the LU, CS, and VE groups when treated with 6 W, whereas the lowest Sa values were obtained for CS when treated with the ME and EM when treated with the ME or 3 W. Only SH and CS indicated a significant correlation between surface rough ness and bond strength.
Conclusions: Er:YAG laser etching is comparable to micro-abrasion when treating resin composite blocks and may induce fewer surface cracks. HF etching remains the gold standard for the treatment of glass-based ceramics and PICNs.

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Purpose: This study was performed to examine how denture wearing improves jaw and neck muscle coordination during chewing in partially edentulous elderly patients.
Methods: Sixteen patients classified as Eichner’s index B2 or B3 and 16 young dentate subjects were enrolled. Jaw and neck muscle activities during chewing were recorded using electromyography with and without denture wearing, then analyzed using intermuscular Electromyography (EMG)-EMG transfer and EMG-EMG coherence function analyses to clarify quantitative, temporal, and functional coordination of jaw and neck muscle activities while chewing. Occlusal force and masticatory scores were also determined.
Results: Denture wearing increased the power values for jaw closing muscle activities, and improved occlusal area and force, and masticatory score. Gain values for jaw closing and opening muscle activities were decreased in those wearing dentures compared to those not wearing dentures. Denture wearing resulted in equivalent gain values for jaw closing and opening muscle activities as compared to the young subjects. Coherence values for chewing and non-chewing side neck muscle activities were increased as compared to not denture wearing.
Conclusions: The suitability of denture wearing can be evaluated from the viewpoint of gain as a quantitative parameter showing coordination between jaw closing and opening muscle activities. Such evaluation can be performed from the viewpoint of coherence as a parameter of functional coordination between jaw and neck muscle activities during chewing in partially edentulous elderly patients. The gain parameter in regard to jaw muscle activities may be compensated to a state equivalent to that seen in young subjects by wearing an appropriate denture.

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Purpose: The aim of this retrospective cohort study was to investigate the long-term outcome of metal- and all-ceramic resin-bonded fixed dental prosthesis (RBFDP) up to 17 years, and to evaluate potential factors influencing the risk for complications.
Methods: Patients who were treated with RBFDP to replace teeth in the anterior or first premolar region in an university setting were identified from electronic records. Data collection comprised dental and periodontal parameters, periapical radiographs, and assessment of the RBFDP. Patient-reported satisfaction was evaluated on visual analog scales (VAS), and 5-year cumulative survival and success rates were calculated. Cox regression models were used to compare metal- versus all-ceramic RBFDPs.
Results: Seventy-one patients with RBFDP replacing 65 anterior teeth and 6 premolars were included with a mean observation period of 56.1 (±42.7) months. RBFDP cumulative survival rate was 86.7% and cumulative success rate 71.7% after 5 years, with no significant difference between metal-and all-ceramic RBFDPs. The risk for RBFDP failure was significantly higher with more than one pontic (OR 6.1; p=0.033), or negative pulp vitality testing of abutments (OR 7.3; p=0.042), while complications tended to be increased with two-wings compared to one-wing RBFDP (OR 5.4; p=0.054).
Conclusions: Metal- and all-ceramic RBFDPs facilitated good long-term results, particularly with one-wing, one-cantilever, and vital abutment teeth.

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Purpose: Ionizing radiation therapy (RT) is the main option for head and neck cancer treatment, but it is associated with multiple side effects. This study aimed to evaluate the effect of RT associated with chewing simulation on the surface of human enamel and Yttria-partially stabilized zirconia (Y-TZP).
Methods: Maxillary premolar cusps and Y-TZP slabs were divided in 7 experimental groups: CO: no RT (control); EZ groups had irradiation applied to both, enamel and zirconia samples (simulating restoration prior to RT); E groups had irradiation applied to enamel only (simulating restoration after RT). RT doses were either 30, 50 or 70 Gray (Gy). Enamel cusps were abraded against zirconia slabs in a chewing simulator (CS - one million cycles/ 80 N/ 60 mm/min, 2 mm horizontal path, artificial saliva, 37˚ C). Zirconia hardness was evaluated before CS; zirconia roughness and enamel volume (wear) were evaluated before and after CS. Hardness and wear data were analyzed by one-way Analysis of Variance and Tukey post hoc test. Roughness was analyzed by Repeated Measures test and Bonferroni test (p=0.05).
Results: There was no significant effect of enamel or zirconia irradiation on enamel cusp wear (p=0.226), regardless of the irradiation dose used - up to 70 Gy. Irradiation also did not affect Y-TZP surface roughness (p=0.127) and hardness (p=0.964).
Conclusions: RT does not promote significant changes to the surface characteristics of zirconia. Irradiated enamel abraded against zirconia does not show higher wear volume when compared to non-irradiated enamel.

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Purpose: The purpose of this study was to compare the correlation between the learning effect of dental computer-aided design (CAD) software and computer literacy in the clinical and preclinical experience groups of computer-aided design and computer-aided manufacturing (CAD/CAM).
Methods: A total of 28 participants were recruited, including 14 dental students and 14 dental technicians. Their working time was evaluated using a custom abutment design with two dental CAD software program (exocad GmbH and Deltanine). The working time of custom abutment design was measured 3 times. A survey was conducted to evaluate the computer literacy. For statistical analysis, Mann–Whitney U test was used to analyze the difference between the clinical and preclinical experience groups and the correlation between computer literacy and reduction in working time was confirmed by Spearman's Rank correlation analysis (α=.05).
Results: The median working time showed the clinical experience group had faster than the preclinical experience group (P<.001). On the other hand, the reduction in working time was higher in the preclinical experience group (P=.002). Only preclinical experience group had a significant positive correlation between the computer literacy and reduction in working time (P<.001).
Conclusions: Basic computer skills are required for first-time users to achie ve an excellent learning effect of dental CAD software program.

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Purpose: Wearing a sports mouthguard is not only recommended in collision sports, such as American football, boxing, and rugby football, but also in low-contact sports, such as basketball, handball, and soccer. It is recommended to remove oral prosthetic devices while playing sports to avoid the risk of fracturing the device. However, players with maxillectomy must wear obturator-type prosthetic devices for speech, breathing, and deglutition even while playing sports. Therefore, there is a need for an oral appliance to prevent dental injury while playing sports without the risk of fracturing the device for players who have undergone maxillectomy.In this case, we fabricated and proposed overlay-type and obturator-type customized sports mouthguards for a patient who had undergone maxillectomy and assessments of satisfaction, speech intelligibility, nasopharyngeal closure function, and swallowing function while playing soccer.
Results: The patient was only satisfied with the obturator-type mouthguard, and the results of the speech intelligibility, nasopharyngeal closure function, and swallowing tests using the obturator-type mouthguard showed no differences compared to those associated with the previously used prosthetic device.
Conclusions: This case may help highlight the importance of providing obturator-type mouthguards for players who have undergone maxillectomy to prevent dental injury and physical and mental discomfort.

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