In this study, we experimentally produced some types of temporary carboxylate cement containing a combination of HY-agents: zinc fluoride, fluorinated strontium, and tannic acid. Cement samples were then tested for antibacterial activity against Streptococcus mutans and Actinomyces naeslundii. The results showed that temporary cements of all types exhibited antibacterial activity. A comparison of cases with and without temporary carboxylate cement revealed a higher level of antibacterial activity with temporary carboxylate cement. Because the cement with zinc fluoride exihibited the highest level of antibacterial activity against S. mutans, the results suggest that zinc fluoride can enhance the antibacterial activity of commercial temporary carboxylate cement containing a combination of HY-agents. A combination of zinc fluoride, fluorinated strontium, and tannic acid showed the same level of antibacterial activity against A. naeslundii. The results reveal that the enhanced anti-bacterial activity of commercial temporary carboxylate cement with HY-agents can be attributed to their synergistic effect.
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