We evaluated heparinoid-containing soft ointments and heparinoid-containing creams to develop information useful to select drugs. Spreadability, consistency and the water content of stratum corneum was measured. A selection table focusing on impression of the use was prepared. Spreadability of the semi-original soft ointment and cream were lower than those of all generic drugs. Regarding hardness, one generic soft ointment was softer than the semi-original drug, but the semi-original cream was harder than all generic creams. Regarding the impression of the use, a significant difference was noted in smell in soft ointments, and 6 items in creams. Correlation was found between the spreadability and consistency test results and impression of the use. A significant difference was noted in the water content of stratum corneum in creams. The selection table prepared based on the impression of the use may provide information that helps selection of preparations in clinical practice.

For seventeen months, a pharmacist visited an elderly care facility with the family doctor and continuously monitored a patient who was receiving medication. In July and August 20XX, this patient was hospitalized because of asymptomatic cerebral infarction. She had been receiving treatment for Lewy body dementia at the facility. After release from hospital in September and October 20XX, she repeatedly, developed dermatitis, whenever a rivastigmine patch was used. Also, her symptoms of parkinsonism, such as muscular rigidity, was not seen to improve. Rather, her symptoms worsened. In November 20XX, when the doctor and pharmacist visited her for diagnosis, the pharmacist told the doctor that her dermatitis was severe. The patient’s prescription was changed from rivastigmine patches to galantamine (8mg/day). In January the following year, the family doctor increased the dose of galantamine to 16mg/day. After that, she was hospitalized for feeling nausea, in February of that year. The administration of galantamine was stopped and she returned to her elderly care facility in April of that year. The pharmacist in charge suggested the doctor prescribe a low dose of galantamine as some improvement in her symptoms were observed in December 20XX. The pharmacist recorded the patient’s condition on an analogue scale and made an assessment based on the NM scale and N-ADL using medication history and information from caregivers at the facility. As a result, it became clear that there is some possibility of improving Lewy body dementia by the long-term administration of low-dose galantamine without any associated side effects.