The purpose of this study was to clarify the clinical effect of cryotherapy using a cold pack after total knee arthroplasty (TKA). Forty-eight knees of 48 patients were randomized into two groups : Those receiving cryotherapy and those receiving no treatment. Subjects were assessed for skin surface temperature, post-operative blood loss, swelling of the bilateral lower limbs, pain, blood parameters (International Normalized Ratio of Prothrombin Time : INR). Skin surface temperature and pain score was recorded just after the operation and at 4, 10, 24, 48 and 72 hours post-surgery. Post-operative blood loss and lower limb swelling was recorded 24, 48 and 72 hours after surgery. Blood was collected on the day prior to surgery and postoperative day 4 to determine INR. Skin surface temperature of cryotherapy group was significantly lower than the temperature of control group. There was no significant difference between two groups in post-operative blood loss and INR. There were no significant differences between the two groups regarding swelling of the lower limbs, measured as the circumference at thigh, mid patella and maximum swelling crus. There was no significant difference between two groups in pain score that measured by using the Visual Analog Scale. It was suggested that there was no beneficial effect for skin surface temperature of knee, post-operative blood loss, swelling of the lower limbs, INR, pain in cryotherapy using a cold pack in 72 hours after total knee arthroplasty.
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