For two infertile couples with normal tubal function and spermatogenesis, who were diagnosed with infertility attributed to lack of competent ovum with poor grade embryo in spite of having received timing therapy and step-up therapy (artificial fertilization from husband ; AIH and in
vitro fertilization and embryo transfer ; IVF-ET), Kampo-only therapies diagnosed according to their “
Zheng” syndrome-type consisting of one cycle of tokishigyakukagoshuyushokyoto, and two cycles of kamishoyosan and anchusan was performed. As a result, both women became pregnant and gave live births. The causes of infertility in these two cases were analyzed, and problems with step-up therapy, commonly used in Western medicine and efficacy of Kampo-therapy diagnosed according to their
Zheng were evaluated from the standpoint of Western medicine.
Kampo-therapy diagnosed by
Zheng was found to improve the follicular and luteal functions as well as related functions. The two cases presented were diagnosed as infertile due to ovarian dysfunction on the basis of therapeutic diagnosis. The indications of IVF-ET are tubal and male infertilities, not to be ovarian dysfunctional infertility.
For infertility due to ovarian dysfunction, Kampo-therapy diagnosed by
Zheng with
Kuoketsu and
Risui effects are drugs of first choice, rather than clomiphene, which has an anti-estrogen activity.
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