Taste disorders can be caused by various factors, including zinc deficiency, adverse drug reactions, colds, stress and xerostomia. The number of patients seeking medical assistance for such disorders is increasing. However, because taste disorders are often difficult to treat, some medical institutions do not provide adequate treatment. A clinic was opened in the Department of Otolaryngology at Osaka Dental University Hospital, on September 1,2004, to treat patients with taste disorders.
We examined 10 patients who had taste disorders associated with xerostomia but no subjective symptoms for other otolaryngological diseases. Although four of them had been prescribed zinc by other physicians, only two actually had zinc deficiency. Zinc administration did not improve the symptoms in any of the patients. Based on the diagnostic criteria of our department, 9 of the patients had xerostomia, 4 of whom were diagnosed with Sjögren's syndrome. When these 9 patients were instructed to gargle with cevimeline hydrochloride, taste sensation improved in 8 of them.
We concluded that latent Sjögren's syndrome should be suspected in patients presenting with taste disorder with xerostomia, and that gargling with cevimeline hydrochloride appears beneficial in these individuals.
View full abstract