(1) 馬の水抽出脾臓蛋白質から,50°の熱処理後,硫安飽和(10)～(40)の分別沈澱法によつて,0.15%の収量でferritinを結晶状に単離確認した.
(2) Ferritinの等電点は,そのpH-mobility曲線から約pH=4.4であつた.
(3) Ferritinの鉄含量の偏差を認め,これについて考察した.
(4) pH=3.6以下の酸性側に於けるferritinの電気泳動図の攪乱について考察した.
(5) Ferritinは280mμに吸収帯を有し, 268, 295, 305, 440mμにも多少の彎曲点を有していた.
本実験について御指導と御鞭撻を賜つた京都大学近藤金助教授に深甚の謝意を表する.

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シャーガス病は中南米に広く分布する深刻な感染症であるが、域内対策イニシアチブが成果を挙げ、5カ国で感染の中断が「認定」されている。米州保健機構 (PAHO) が支援する対策イニシアチブのモニタリング・評価は「域内年次会議」と「PAHO評価団」を中心に実施される。このモニタリング・評価の目的には目標達成度の評価のみならず技術交換やキャパシティ・ビルディングも含まれ、各国やドナー機関の関係者が広く参加して実施される。
国際協力機構 (JICA) が協力するグアテマラ国シャーガス病対策は域内イニシアチブのモニタリング・評価に参加することで (ア) PAHO・グアテマラ・JICA間の相互強化、(イ) 関係者の能力向上、(ウ) 域内協力の活性化、等の利益があった。シャーガス病対策のモニタリング・評価は技術面に限られており、今後はJICAとPAHOが相互補完して包括的な評価をすることが望まれる。

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We reported that thrombokinetic study was useful to detect early stage of platelet plug formation and adhesion in vivo on the cases of thrombocytosis Blood and Vessel 8 (2), 193-198, 1977. Afterward we added more cases with risk factors of thrombogenesis and discussed about their significance by means of throm bokinetic study.
Clinical studies. A total of 28 cases were studied, composed of 24 cases of cardio-valvular replacement, 2 cases of vascular disorders and 2 cases of diabetes mellitus with retinopathy. The result of this study showed that platelet survival in cases without thrombosis was almost normal but was significantly shortened in cases with thrombogenic episodes (2 cases of chronic myelogenous leukemia (CML), 1 case of myelofibrosis with myeloid metaplasia (MMM), 1 case of primary thrombocythemia). The shortened platelet survival time implied increased platelet consumption for thrombus formation.
We measured von Willebrand factor activity, and FVIII related antigen (FVIII AGN) in cases of vascular disorders (34 cases of diabetes mellitus with retinopathy, 10 cases of hypertension). Diabetes mellitus with retinopathy were proved to have high vWF activity and high VIII AGN value. On the other hand, hypertension with retinopathy showed high vWF activity but normal FVIII AGN value.
In 2 cases of diabetes mellitus with retinopathy, platelet survival time was significantly shortened.
These results suggested that increased FVIII AGN might initiate and produce vascular change and resulted in platelet consumption and thrombus formation.
Experimental studies.
SHR (spontaneously hypertensive rat) was used as the experimental model of hypertension. We studied platelet survival time on spontaneously hypertensive ratstroke prone (SHR-SP) and spontaneously hypertensive rat-stroke resistant (SHRSR) by means of in vivo labelling with ⁷⁵Se-Selenomethionine.
The result of this study showed that significantly short survival was observed in SHR-SP of 10 weeks of age compared with SHR-SR.
Platelet seems to have some concern with elevation of blood pressure and producing vascular alteration on SHR-SP.

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ホップ樹脂の抗菌作用によりPediococcus cerevisiae(いわゆるbeer-sarcina)はビール中において形態の異常をきたし,直径で15倍,体積で3000倍にもなることを確認した.
この巨大細胞の形状は球形で,まれに楕円形を呈し,見掛上酵母と類似しているが,染色により両者をかんたんに区別できることを知った.
巨大細胞はグラム陽性を維持し,クロマチンよう物質及び細胞壁も存在するが,細胞壁は異常で正常の球菌細胞に比しこわれ易い.

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An imaging system based upon the peel apart procedure has been described elsewhere. The imaging structure consists of a photochemically active layer comprising a polymer and a photosensitive material such as an azide compound, a thin metal layer deposited on a substrate and a cover film. After imagewise exposure and following heating, peeling of the cover film off the base forms a metal pattern on the base film.
In this paper, characteristics of a negative working type structure which used 1, 4-naphthoquinone and vinylchloride-vinylacetate-maleic acid terpolymer (P-VCVAcMAc) was studied by changing various process conditions and the results were compared with the positive working case in which azide compounds and polyvinyl chloride were used. It was found that the image could not be formed if heated after exposure at a temperature above 50°C or if stored longer than a day in the negative working design.
In the positive working system, good metal images were obtained with surface-cleaned aluminum layers as well as with untreated ones. In the negative type imaging, however, images were not developed by use of the cleaned surfaces. These results were explained in terms of changes in the peeling strength between the photosensitive polymer layer and the aluminum sheet subjected to the surface treatments. It was suggested that reduction of adhesive strength by surface contamination must be helping the image formation.
Surface inspections of aluminum sheets indicated that the surface became much planer by electropolishing. From results of contact angle measurements, it was considered that fresh and clean oxidized layer appeared on the aluminum surface by this treatment.
A possible explanation of imaging mechanism was proposed that in the positive type imaging the hydrogen bonds at the metal/photosensitive polymer layer interface are newly formed by polar photolytic products, whereas in the negative type imaging hydrogen bonds at the same interface are destroyed by photochemical products.

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小麦については,安定供給のため種子の貯蔵が行われており,前年産の種子が生産現場に配布されることもしばしばある.そこで,2014年に採取した収穫時の穀粒水分が異なる種子について,1年貯蔵後の発芽率を調査したところ,1年間の適切な保存であれば発芽率に影響を及ぼさず,収穫時の水分は種子の保存性に影響を及ぼさなかった. 実際の小麦栽培では土壌水分などが苗立ちに影響することが想定される.そこで,ポット試験で湛水処理を変え,発芽率の異なる小麦種子について,土壌水分の違いが苗立率に及ぼす影響を調査した.土壌に播種すると,生産物審査の方法による発芽率に比べて,苗立率は低下した.発芽率に対する苗立率の低下割合は,発芽率の高いものほど小さく,発芽率の低下に伴って大きくなった.また,種子下3～4cmまで湛水すると,無処理と比べて苗立率は低下し,発芽率の低いサンプルほど苗立率の低下割合が大きくなった.これらのことから,苗立ちを確保し小麦を安定生産するためには,発芽率の高い優良種子の生産が重要であることが確認できた.

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