Rubella HI antibody titer was estimated among 302 child-bearing age women, 14 young male adults and 65 children. After the epidemic in 1975-1976, distribution of antibody titer was studied in the same group.
In young adults, sero-positive rate is 66.1% before, and 73.3% after the epidemic.
Infection-rate and symptomless infection-rate is 10.5% eithes.
In children, HI antibody titer in different agegroups prior to and after the epidemic is as following. 0-1 yr: 0-0%, 2-3 yr: 0-40.0%, 4-5 yr: 0-50.0%, 6-7 yr: 13.3-33.3%, 8-9 yr: 23.1-46.2%, and 10-15 yr: 27.2-36.4%.
After this epidemic, antibody titer did not elevated in 70% of sero-negative children.
In rubella epidemic, the children suffered from other virus infection are to be diagnosed as rubella some times. In 5 yr girl complaining slight fever, milliar paples appeared on her abdomen. The cervical and occipital lymphnodes were palpable. Her two brothers were suffered from rubella about 1 month and 2 weeks prior to her episode respectively. So she was strongly suspected as rubella, but rubella HI titer was below 1: 8 in her pair serum. Adeno, ECHO, or Cox CF antibody was not detected.
In our observation in this epidemic, we had 9 cases who were suspected as rubella but negative rubella HI titer. 3 of these 9 cases were measles. 2 were adeno virus infection. Serological test is essential for established diagnosis.
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