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9pSE-5 Hydrodynamical Model and Hard Probe

平野哲文

日本物理学会講演概要集
2003年 58.2.1 巻
発行日: 2003/08/15
公開日: 2018/03/03

DOI https://doi.org/10.11316/jpsgaiyo.58.2.1.0_48_2

会議録・要旨集フリー

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ニッケル基ろうによるステンレス鋼のろう接継手強さについて

川勝一郎, 大沢直, 斉藤晴久

日本金属学会誌
1979年 43 巻 11 号 1001-1007
発行日: 1979年
公開日: 2008/04/04

DOI https://doi.org/10.2320/jinstmet1952.43.11_1001

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Mechanical properties of the brazed stainless steel joints with nickel base filler metals (
BNi
) were studied in relation to the microstructures at the brazing interface. The filler metals used for this experiment were
BNi
-1,
BNi
-3 and
BNi
-7.
In this study the brazing phenomena on stainless steel joints with
BNi
filler metals were discussed from the viewpoints of brazability, shear strength of lap brazed joints at room temperature and elevated temperatures, and the effects of diffusion treatment on the brazed joints. The results obtained are summarized as follows:
(1) The
BNi
filler metals showed satisfactory brazability for stainless steel, and especially
BNi
-7 were excellent.
(2) A defect of the brazed joints with
BNi
filler metals existed in the brittleness at room temperature. But at elevated temperatures the shear strength of the joints were remarkably improved.
(3) The brazed joints with
BNi
-1 and
BNi
-3 filler metal were improved in shear strength by the diffusion treatment.
(4) The long time brazing process was effective for improving the mechanical strength of the joints.
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Biological nitrification inhibition (
BNI
)—Is there potential for genetic interventions in the Triticeae?

Guntur Venkata Subbarao, Masahiro Kishii, Kazuhiko Nakahara, Takayuki Ishikawa, Tomohiro Ban, Hisashi Tsujimoto, Timothy S. George, Wade L. Berry, C. Tom Hash, Osamu Ito

Breeding Science
2009年 59 巻 5 号 529-545
発行日: 2009年
公開日: 2009/12/22

DOI https://doi.org/10.1270/jsbbs.59.529

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The natural ability of plants to release chemical substances from their roots that have a suppressing effect on nitrifier activity and soil nitrification, is termed ‘biological nitrification inhibition’ (
BNI
). Though nitrification is one of the critical processes in the nitrogen cycle, unrestricted and rapid nitrification in agricultural systems can result in major losses of nitrogen from the plant-soil system. This nitrogen loss is due to the leaching of nitrate out of the rooting zone and emission of gaseous oxides of nitrogen to the atmosphere, where it causes serious pollution problems. Using a newly developed assay system that quantifies the inhibitory activity of plant roots (i.e.
BNI
capacity), it has been shown that
BNI
capacity is widespread among crops and pastures. A tropical pasture grass, Brachiaria humidicola has been used as a model system to characterize
BNI
function, where it was shown that BNIs can provide sufficient inhibitory activity to suppress soil nitrification and nitrous oxide emissions. Given the wide-range of genetic diversity found among the Triticeae, and the current availability of genetic tools for moving traits/genes across members, there is great potential for introducing/improving the
BNI
capacity of economically important members of the Triticeae (i.e. wheat, barley and rye). This review outlines the current status of knowledge regarding the potential for genetic improvement in the
BNI
capacity of the Triticeae. Such approaches are critical to the development of the next-generation of crops and production systems where nitrification is biologically suppressed/regulated to reduce nitrogen leakage and protect the environment from nitrogen pollution

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ステンレス鋼製熱交換器用Ni ろうの腐食挙動

深井祐佑, 荘司郁夫, 小林竜也, 安藤哲也, 吉田拓也, 柏瀬毅, 大友昇

スマートプロセス学会誌
2020年 9 巻 3 号 127-132
発行日: 2020/05/10
公開日: 2020/05/27

DOI https://doi.org/10.7791/jspmee.9.127

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To investigate the corrosion behavior of the stainless steel joints brazed with nickel-based brazing filler metals in the heat exchanger, electrochemical measurement of SUS316L and filler metals were carried out.
BNi
-5 (Ni-Cr-Si alloy) and FP-613 (Ni-Cr- P-Si alloy) filler metals were prepared as nickel-based brazing filler metals. Corrosion potential, galvanic current and polarization curves of SUS316L,
BNi
-5 and FP-613 were measured in a 0.06 mol/L NaCl solution at 25℃ and 80℃. After the measurement, the microstructures of specimens were observed with an electron probe X-ray micro analyzer (EPMA). As a result, it was found that
BNi
-5 preferentially dissolves in the SUS316L joint with
BNi
-5 filler, and SUS316L preferentially dissolves in the joint with FP-613 filler in the NaCl solution. The EPMA analysis clarified that Si-rich Ni-Si-Cr-Fe phases and the Cr and P-rich phases preferentially dissolve in
BNi
-5 and FP-613, respectively.
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作物による土壌の硝化抑制で地球環境にやさしい効率のよい食料生産を

吉橋忠

沙漠研究
2023年 32 巻 4 号 133-139
発行日: 2023/03/30
公開日: 2023/03/30

DOI https://doi.org/10.14976/jals.32.4_133

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高い生物的硝化抑制（
BNI
）能を持つ野生コムギ近縁種であるオオハマニンニクとの属間交配により，多収品種に
BNI
能を付与した
BNI
強化コムギを開発した．
BNI
強化コムギは圃場において，土壌中のアンモニア態窒素の硝化を遅らせ，その土壌中濃度を向上させ，低窒素環境でもコムギの生産性が向上し，コムギの窒素利用効率が向上する．
BNI
強化コムギにより，生産力を維持しつつ，施肥窒素量の低減と窒素による環境汚染軽減が期待できる．

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高温NaCl水溶液中におけるニッケルろう
BNi
‐5の電気化学的挙動

境昌宏, 中川翔太

Zairyo-to-Kankyo
2015年 64 巻 5 号 197-200
発行日: 2015/05/15
公開日: 2015/11/11

DOI https://doi.org/10.3323/jcorr.64.197

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オーステナイト系ステンレス鋼製の熱交換器ニッケルろう付け部の耐食性を調べるために，ステンレス鋼SUS316Lおよびニッケルろう
BNi
‐5の電気化学的測定を行った．0.06 mol/L NaClおよび0.06 mol/L Na₂SO₄水溶液中において，室温および80℃下でSUS316Lと
BNi
‐5の自然腐食電位，ガルバニック電流を測定した．80℃のNaCl溶液中における
BNi
‐5の自然電位は室温時のそれよりも低下するが，SUS316Lの自然電位は室温と80℃下でほとんど差は生じない．NaCl溶液中でのSUS316Lの自然電位は
BNi
‐5のそれよりも貴であった．80℃のNaCl溶液中におけるSUS316Lと
BNi
‐5との電位差は最大約0.4Vであった．NaCl溶液中でSUS316Lと
BNi
‐5とのガルバニック対に流れるガルバニック電流は，室温ではほぼゼロであり，80℃では最大約0.2 μA/cm²であった．Na₂SO₄溶液中ではSUS316Lと
BNi
‐5との間に室温，80℃下においてガルバニック電流はほとんど流れなかった．
BNi
‐5とSUS316Lとのガルバニック腐食は，高温の塩化物イオンを含む溶液中で生じる恐れがあることが明らかとなった．
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低シリコン含有ニッケル基ろうの開発研究

渡辺健彦, 若月健, 柳沢敦, 佐々木朋裕

溶接学会論文集
2011年 29 巻 4 号 241-247
発行日: 2011年
公開日: 2011/10/24

DOI https://doi.org/10.2207/qjjws.29.241

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Authors tried to develop a new nickel-based brazing filler metal containing no boron and phosphorous to suppress the formation of brittle phases in a brazed layer. The properties of a joint brazed using the new filler metal were investigated and compared with those of a brazed joint using a conventional nickel-based filler metal of
BNi
-5. The following results were obtained in this study.
A new nickel-based brazing filler metal was successfully developed, which contains a small amount of Si and Mn and shows the melting temperature lower than about 1090°C. The hardness of the new filler metal was about 40% that of
BNi
-5 filler metal containing about 10% Si.
In brazing of SUS304 stainless steel, using
BNi
-5 filler metal, a hard and brittle finally-solidified region appeared in the brazed layers with joint clearance over 100μm. However, using the new filler metal, the finally-solidified region appeared in the brazed layers with joint clearance over 200μm. The hardness of the finally-solidified region in the brazed layer using the new filler metal was about 54% that using
BNi
-5 filler metal.
The tensile strength of a SUS304 joint brazed using
BNi
-5 filler metal extremely decreased at joint clearance over 100μm. On the other hand, the tensile strength of a joint brazed using the new filler metal decreased at joint clearance over 200μm. It seems that the brittle finally-solidified region formed in a brazed layer causes the joint to decrease the tensile strength.
It was shown that the newly developed filler metal is superior to the conventional
BNi
-5 filler metal in hardness and in tensile strength of joints with wider joint clearance.
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アロイ800の液相拡散接合用インサート金属の開発

数理計画法による接合用インサート金属組成の最適化(第1報)

中尾嘉邦, 西本和俊, 藤谷泰之

溶接学会論文集
1994年 12 巻 4 号 539-546
発行日: 1994/11/05
公開日: 2009/06/12

DOI https://doi.org/10.2207/qjjws.12.539

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This report presents a new alloy-designing technique to develop the insert metal for liquid diffusion bonding. A mathematical programming method was developed by modifying the method in two dimensions proposed by I.P. Schagen into multi dimensions. The main procedure of this method is to obtain the optimum point to maximize some index of an objective performance by calculation from the limited experimental data using interpolation. An interpolating function which yields a curved surface passing on all the specified data points was determined assuming the values of data were normally distributed. If the curved surface is once obtained, its general view will give suggestions for further searches and the optimum point can be efficiently searched. This method has been applied for developing the insert metal for liquid diffusion bonding of Alloy 800. As for the candidate insert metals, alloys which had similar composition to that of Alloy 800, but contained some amounts of silicon, boron and carbon as the depressant elements were chosen. The objective function which was introduced as an index of the performance of insert metals involves the melting point, the strength (hardness) and formability of brittle phases in the bonding interlayer as the evaluating factors. Through calculation based on twenty three experimental date, a composition of Fe-20Cr-30Ni-1.5B-0.75C-4Si which optimized the objective function was determined. Scanning electron microscopic analysis revealed that the joint bonded with the newly developed insert metal (Fe-20Cr-30Ni-1.5B-0.75C-4Si) had a sound microstructure without forming brittle phases in the bonding interlayer. This joint also exhibited good tensile properties, that is, its strength and ductility were comparable to those of the base alloy.
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Footshock- and Psychological-Stress Prevent the Development of Tolerance to Spinal but Not Supraspinal Morphine

Masakatsu Takahashi, Hiroshi Kaneto

The Japanese Journal of Pharmacology
1991年 56 巻 2 号 121-126
発行日: 1991年
公開日: 2006/07/11

DOI https://doi.org/10.1254/jjp.56.121

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The site of action involved in the suppression by exposure to footshock (FS)- and psychological (PSY)-stress of the development of antinociceptive tolerance to morphine has been investigated. Daily treatment with 10 mg/kg, s.c.; 3μg, i.t.; and 5μg, i.c.v. of morphine, regardless of the administration route, resulted in the development of tolerance. Daily exposure to FS- or PSY-stress suppressed the development of tolerance to s.c. and i.t. administered morphine but not that to i.c.v. administered morphine. Pretreatment with 2 mg/kg, i.p. of nor-binaltorphimine (nor-
BNI
) abolished the suppressive effect of PSY-stress on the development of tolerance to morphine given s.c. The suppression by PSY-stress was also antagonized by 2μg, i.t. of nor-
BNI
and not by 2μg, i.c.v. of nor-
BNI
. Thus, the development of tolerance in the spinal cord due to interaction of morphine at μ-opioid receptors can be suppressed by exposure to these stresses, probably through the descending signals from the supraspinal area, and activation of κ-opioid receptors in the spinal cord could also participate in the suppression by PSY-stress.
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Pharmacological Study on the Novel Antinociceptive Agent, a Novel Monoterpene Alkaloid from Incarvillea sinensis

Yu-Ming Chi, Motoyuki Nakamura, Toyokichi Yoshizawa, Xi-Ying Zhao, Wen-Mei Yan, Fumio Hashimoto, Junei Kinjo, Toshihiro Nohara, Shinobu Sakurada

Biological and Pharmaceutical Bulletin
2005年 28 巻 10 号 1989-1991
発行日: 2005年
公開日: 2005/10/01

DOI https://doi.org/10.1248/bpb.28.1989

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To determine the antinociceptive mechanism of incarvillateine (INCA), the opiate antagonists nor-binaltorphimine (nor-
BNI
), β-funaltrexamine (β-FNA) and naltrindole (NTI) were pretreated prior to its injection in a formalin test. The antinociceptive effect of INCA was antagonized by nor-
BNI
(κ-receptor antagonist) and β-FNA (μ-receptor antagonist), while NTI (δ-receptor antagonist) did not influence its effect. Furthermore, the antinociceptive effect of INCA was blocked by theophylline (THEO), an adenosine-receptor antagonist. These results suggested that the antinociceptive effect arose from the activation of μ-, κ-receptors and adenosine-receptor.
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インサート金属組成の最適化による高温接合継手特性の改善

HP系耐熱鋳鋼の液相拡散接合に関する研究(第2報)

西本和俊, 才田一幸, 望月暁久, 乾正弘, 高橋誠

溶接学会論文集
1997年 15 巻 2 号 344-351
発行日: 1997/05/05
公開日: 2009/06/12

DOI https://doi.org/10.2207/qjjws.15.344

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Improvement in mechanical properties of transient liquid phase (TLP) bonded joints of HP alloy at the elevated temperature was investigated employing newly developed insert metal. TLP-bonding was carried out at 1403-1463 K for 600s in vacuum. The chemical compositions of insert metal were optimized by the mathematical programming method. The objective function which was introduced as an index of performance of insert metals involved the melting point of insert metal, the strength (hardness) and formability of microconstituents in the bonding layer as the evaluating factors. A composition of Ni-3% Cr-4% Si-3% B which optimized the objective function was determined. SEM observation revealed that the microstructure in bonding layer using the newly developed insert metal indicated a sound morphology without forming microconstituents such as Cr₇ (C, B)₃. The tensile properties of joint at 1273 K were comparable to those of base metal in the bonding temperature range of 1423-1463 K. The fractured of the joints bonded at 1423-1463 K occurred in the base metal substrate, while the joint bonded at 1403 K, which tensile properties were fairly deteriorated compared with the base metal, fractured at the bonding interface.
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Ni-Cu基ろうによるステンレス鋼ろう付継手の機械的特性

斎藤慎二, 茅本隆司, 恩澤忠男

溶接学会論文集
1999年 17 巻 1 号 35-40
発行日: 1999/02/05
公開日: 2009/06/12

DOI https://doi.org/10.2207/qjjws.17.35

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In brazement with nickel filler metal, the formation of brittle phase degrades the reliability and the strength of the joint. This phase is composed of melting temperature depressants in the filler metal, such as silicon, boron or phosphorus. In particular, this phase tends to form in brazed joint with a wide clearance. In order to avoid the formation of the brittle phase, a strict control of brazing clearance is required, which is kept as narrow as possible during the brazing process. In some cases, however, such a strict control may be difficult.
The purpose of this study is to develop the filler metals free of or less in silicon, boron and phosphorus, thereby suppressing the formation of the brittle phase. The nickel-copper alloy was chosen as the bass alloy of the filler metal, and two kinds of Ni-Cu-Sn-Si and Ni-Cu-Mn-Si filler metals were developed. The experiments were carried out to investigate the mechanical properties of the joints brazed with these filler metals.
The tensile test of butt joints of SUS316 stainless steel brazed with developed filler metals was conducted, whose clearance were in the range of 10 to 100 micrometers. Hardness distributions of the brazed joints were also measured. Same experiments were carried out on the brazed joints with
BNi
-2 and
BNi
-5.
The tensile strength of the Ni-Cu-Sn-Si filler brazed joints was about 500 MPa for the clearance of 10μm and was about 300 MPa for 100μm. In the joins with the Ni-Cu-Mn-Si filler metal, the tensile strength was about 600 MPa for 10μm and 350 MPa for 100 μm. In the joints of clearance more than 50 μm, tensile strength of the developed filler metals were superior to those of
BNi
-2 and
BNi
-5, in which the hardness of the joints increased obviously.
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228 高周波誘導加熱を用いたステンレス鋼管のろう付圧接に最適なろう材の開発(溶接・接合)

鈴村暁男, 千木崎俊太郎, 池庄司敏孝, 山崎敬久

機械材料・材料加工技術講演会講演論文集
2006年 2006.14 巻 228
発行日: 2006/11/25
公開日: 2017/06/19

DOI https://doi.org/10.1299/jsmemp.2006.14.123

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Braze Pressure Welding (BPW) with high frequency induction heating is a newly developed pressure welding technique using brazing filler as interlayer metals for welding the general steel pipes for pipe arrangement in buildings. In this report, stainless steel pipes were joined by BPW with some kinds of interlayer metals, and the joint of the pipes made by BPW were evaluated by microscopy, element profiles and tensile strength of the joints in order to determine the suitable interlayer metal for BPW of stainless steel pipes. As the result of this research, the BPW joint using
BNi
-2 as interlayer metal was stronger with less melting of base metal than that of the
BNi
-5. A newly developed Fe-base interlayer metal was also suitable for BPW of stainless steel pipes.
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The CGIAR–JIRCAS Partnerships for Sustainable Food Systems: Rice Blast Differential Systems and Biological Nitrification Inhibition as Examples

Satoru MURANAKA, Yoshimichi FUKUTA, Guntur V. SUBBARAO, Tadashi YOSHIHASHI

Japan Agricultural Research Quarterly: JARQ
2021年 55 巻 Special 号 501-509
発行日: 2021/12/01
公開日: 2022/02/10

DOI https://doi.org/10.6090/jarq.55.501

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The Japan International Research Center for Agricultural Sciences (JIRCAS) working with partners such as CGIAR and its research centers, has made notable progress in creating farming solutions directed at the needs of poor farmers worldwide. This review discusses two critical achievements—development and deployment of differential systems for blast study in rice and biological nitrification inhibition (
BNI
). Both achievements were initiated from basic studies. Results of the research guide crop improvement programs designed to introgress rice blast resistance and
BNI
into target crops. Both works clearly highlight that collaboration of scientists are key to the success. The wide research networks of JIRCAS and CGIAR are effective at establishing partnerships which can tackle the complexity and geographic scale of challenges in agricultural research. CGIAR’s strong presence in regions where problems occur, rich genetic resources, and strong genetic improvement programs are crucial to effective research-for-development activities to achieve agricultural sustainability. CGIAR–JIRCAS partnerships should be strengthened to bringing the benefits of science to the world’s poor farmers.

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熱交換器用ステンレス鋼のNiろう接合継手の強度と組織

高山智司, 有倉洋平, 荘司郁夫, 中澤崇徳, 松本健, 曳田昌徳

日本金属学会誌
2004年 68 巻 2 号 130-133
発行日: 2004年
公開日: 2005/06/24

DOI https://doi.org/10.2320/jinstmet.68.130

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The influence of exposure to heat after brazing and the plate thickness on the mechanical properties and the microstructures of brazed joints of SUS304 with Ni-based filler (
BNi
-2 filler) has been investigated. Fine Cr-B compounds, with diameters of approximately 5 μm, formed in the brazed joint. The diffusion of Cr and B along the grain boundaries of SUS304 was observed at the joint interfaces. The Vickers hardness of the Cr-B compound and the diffusion layer were approximately double that of the
BNi
-2 filler. The Cr-B compounds disappeared after the exposure to heat of 980°C for 6 h. On the other hand, the growth of the diffusion layer into SUS304 was observed after the exposure to heat. The joint strength was found to be approximately 100 MPa when fracturing occurred in the filler layer with Cr-B compounds and at the joint interface between the filler layer and the diffusion layer. When the thin plates with
BNi
-2 filler were brazed and a stress below 100 MPa was applied to the brazed joint, fracturing occurred not at the brazed joint but in SUS304.
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Catalytic Aerobic Oxidation of nor-Binaltorphimine (nor-
BNI
) Analogs without 4,5-Epoxy Bridge Affords a More Selective Ligand for κ Opioid Receptor than the Representative κ Antagonist nor-
BNI

Yumiko Osa, Yoshihiro Ida, Hideaki Fujii, Toru Nemoto, Ko Hasebe, Shinobu Momen, Hidenori Mochizuki, Hiroshi Nagase

Chemical and Pharmaceutical Bulletin
2007年 55 巻 10 号 1489-1493
発行日: 2007/10/01
公開日: 2007/10/01

DOI https://doi.org/10.1248/cpb.55.1489

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An analog of nor-binaltorphimine (nor-
BNI
) without the 4,5-epoxy bridge, 17,17′-bis(cyclopropylmethyl)-6,6′,7,7′-tetrahydro-6,6′-imino-14β,14′α-dihydroxy-3,3′-dimethoxy-7,7′-bimorphinan (4), which was the precursor of the designed compound 1 as a selective κ₃ opioid receptor antagonist, was catalytically oxidized with oxygen in the presence of platinum to give the 5′-oxo derivative 3 with some other oxidized products. Morphinan derivatives without the 4,5-epoxy moiety were labile to oxygen, although the corresponding 4,5-epoxymorphinan derivatives resisted aerobic oxidation. One of the oxidized nor-
BNI
analogs without 4,5-epoxy bridge, compound 18, showed high affinity and selectivity for κ opioid receptor.
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生物的硝化抑制（
BNI
）能を強化したコムギ系統の育成とヒンドゥスタン平原における展開について

*飛田哲, 岸井正浩, 吉橋忠, Subbarao Guntur Venkata, Kumar Uttam, Kumar Arun Joshi

日本作物学会講演会要旨集
2023年 256 巻
発行日: 2023/09/12
公開日: 2023/09/12

DOI https://doi.org/10.14829/jcsproc.256.0_13

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Acidification in Rhizospheric Soil of Field-Grown Sorghum Decreases Nitrification Activity

Takeshi WATANABE, Satish P. VENKATA, Kanwar L. SAHRAWAT, Suhas P. WANI, Osamu ITO

Japan Agricultural Research Quarterly: JARQ
2015年 49 巻 3 号 245-253
発行日: 2015/07/01
公開日: 2015/08/13

DOI https://doi.org/10.6090/jarq.49.245

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To date, most studies on biological nitrification inhibition (
BNI
) in sorghum have been performed with plants grown in hydroponic systems. However, the current study was conducted to determine whether or not sorghum inhibits nitrification in fields of Alfisols, and clarify the mechanism that results in inhibition of soil nitrification in the field. Nitrification activity in the rhizosphere of sorghum (Sorghum bicolor (L.) Moench) i.e. soil attached to its roots within a few millimeters was measured and compared with those in adjacent bulk soil. Sweet sorghum (6 varieties) and grain sorghum (3 varieties) were cultivated in 4 Alfisol fields in a semi-arid tropical region of India during the 2010 or 2011 rainy seasons. Soil samples were collected three times during the growing season. Nitrification activity in the rhizospheric soil was significantly lower than that in the bulk soil during 8 out of 12 samplings while the pH (H₂O, 1:2) of the rhizospheric soil was significantly lower than that of the bulk soil in 10 out of 12 samplings. Acidification of the soil by sulfuric acid decreased the nitrification activity to a comparable extent, as emerged in the rhizospheric soils. Our results indicate that acidification of soil around roots would be one of the main causes of nitrification inhibition by sorghum in the field.
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インサート材を用いた抵抗圧接法における接合現象の研究

梶原良一, 小倉慧, 小園裕三, 志田朝彦, 舟本孝雄

溶接学会論文集
1985年 3 巻 4 号 683-690
発行日: 1985/11/05
公開日: 2009/06/12

DOI https://doi.org/10.2207/qjjws.3.683

ジャーナルフリー

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A resistance pressure welding method using insert material was investigated. In this method, a layer of insert material (
BNi
-2, SUS304, BAg-1) was placed between two base metals to raise electrical contact resistance, and electric current was passed through the layer causing concentrated heating at the interface. The molten layer of low melting point was pressed out of the joint interface. Various types of insert materials were tried for joining SUS304 stainless steel. Metallography of the joint sections was investigated. It was found that
BNi
-2 with high hardness with high hardness and reaction for base metal gave better joint characteristics of high tensile strength, small deformation and homogeneity of the joint layer.
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PARAMETER ESTIMATION IN COX'S REGRESSION MODEL FOR COMPETING RISKS WITH MISSING FAILURE TYPES

Isao Hemmi

JOURNAL OF THE JAPAN STATISTICAL SOCIETY
1995年 25 巻 1 号 81-96
発行日: 1995年
公開日: 2009/01/22

DOI https://doi.org/10.14490/jjss1995.25.81

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Cox's regression model is widely used for analyzing survival data under competing risks as well as for single risk. We consider situations in which failure times are observed but failure types cannot be observed for some individuals. For this kind of incomplete data we propose a two-stage estimator of regression coefficients of covariates based on a pseudo-partial likelihood. We show that this estimator is consistent as the sample size tends to infinity. Simulation studies demonstrate that the proposed estimator for the regression coefficients gives smaller mean square errors than a conventional procedure which regards data with missing failure types as censored when sample sizes are small.
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