Medicinal Flowers. XXXII. Structures of Oleanane-Type Triterpene Saponins, Perennisosides VIII, IX, X, XI, and XII, from the Flowers of <i>Bellis perennis</i>

Toshio Morikawa; Xuezheng Li; Eriko Nishida; Seikou Nakamura; Kiyofumi Ninomiya; Hisashi Matsuda; Makoto Hamao; Osamu Muraoka; Takao Hayakawa; Masayuki Yoshikawa

doi:10.1248/cpb.59.889

Notes

Medicinal Flowers. XXXII.

Structures of Oleanane-Type Triterpene Saponins, Perennisosides VIII, IX, X, XI, and XII, from the Flowers of Bellis perennis

Toshio Morikawa, Xuezheng Li, Eriko Nishida, Seikou Nakamura, Kiyofumi Ninomiya, Hisashi Matsuda, Makoto Hamao, Osamu Muraoka, Takao Hayakawa, Masayuki Yoshikawa

著者情報

Toshio Morikawa
Pharmaceutical Research and Technology Institute, Kinki University
Xuezheng Li
Kyoto Pharmaceutical University
Eriko Nishida
Pharmaceutical Research and Technology Institute, Kinki University
Seikou Nakamura
Kyoto Pharmaceutical University
Kiyofumi Ninomiya
Pharmaceutical Research and Technology Institute, Kinki University
Hisashi Matsuda
Kyoto Pharmaceutical University
Makoto Hamao
Kyoto Pharmaceutical University
Osamu Muraoka
Pharmaceutical Research and Technology Institute, Kinki University
Takao Hayakawa
Pharmaceutical Research and Technology Institute, Kinki University
Masayuki Yoshikawa
Kyoto Pharmaceutical University

キーワード: Bellis perennis, Asteraceae, triterpene saponin, perennisoside, Daisy flower

ジャーナルフリー

2011 年 59 巻 7 号 p. 889-895

DOI https://doi.org/10.1248/cpb.59.889

詳細

抄録

Five new triterpene saponins perennisosides VIII (1), IX (2), X (3), XI (4), and XII (5) were isolated from the MeOH-eluated fraction of the methanolic extract from the flowers of Bellis perennis. The MeOH-eluted fraction of the methanolic extract from the flowers of B. perennis was found to inhibit gastric emptying in olive oil-loaded mice at a dose of 200 mg/kg, per os (p.o.). The stereostructures of 1—5 were elucidated on the basis of chemical and spectroscopic evidence.

責任著者(Corresponding author)

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