Studies on the Constituents of Cimicifuga Species. XV.Two New Diglycosides from the Aerial Parts of Cimicifuga simplex WORMSK.

Abstract

Two new diglycosides (I, II) were isolated from the aerial parts of Cimicifuga smplex (Ranunculaceae), and their structures were determined to be 25-O-acetylcimigenol 3-O-β-D-glucopyranosyl-(1→3)-β-D-xylopyranoside (I) and 23-O-acetylshengmanol 3-O-β-D-glucopyranosyl-(1→3)-β-D-xylopyranoside(II). Two known xylosides (Ia, IIa) were also isolated and identified as 25-O-acetylcimigenol 3-O-β-D-xylopyranoside (Ia) and 23-O-acetylshengmanol 3-O-β-D-xylopyranoside (IIa). Cellulase A [Amano] 3 hydrolyzed I and II to afford Ia and IIa respectively, while Cellulase T [Amano] 4 hydrolyzed I and II to afford 25-O-acetylcimigenol (Ib) and 23-O-acetylshengmanol (IIb) as the aglycones, respectively.