抄録
A surface of gold electrode was modified with a self-assembled monolayer in order to protect the oxidation of ascorbic acid, which exists in biological fluid. The electrode was prepared by the modification with aqueous solution of 5-carboxypentanethiol (5C), 7-carboxyheptanethiol (7C) and 10-carboxydecanethiol (10C). At pH 7.0, alkanethiol modified electrodes did not show any anodic response to ascorbic acid but anodic peak to dopamine and serotonin. Dopamine and serotonin were most selectively oxidized with the 7C-modified electrode prepared in 0.15 mg/ml 7C. The anodic current to dopamine was 500 times higher than that of ascorbic acid. The selective oxidation of dopamine and serotonin was performed by the ionization of alkanethiol.
