合成抗痙攣藥に關する研究

第3報 3-(1, 2, 3, 4-Tetrahydro-S-naphthyloxy) propane-1, 2-diol並びに3-(1, 2, 3, 4-Tetrahydro-7-naphthyloxy) propane-1, 2-diolの藥理作用について (附) 3-(3'-Ethyl phenoxy) propane-1, 2-diol,

抄録

The curarimimetic and anticonvulsant activity activity of 3- (1, 2, 3, 4-tetrahydro-8-naphthyloxy) propane-1, 2-diol (=ar.α-Tetralyl glycerol ether, abbreviated as α-TNP and 3- (1, 2, 3, 4-tetrahydro-7-naphthyloxy) propane-1, 2-diol (=ar.β-Tetralyl glycerol ether, abbreviated as β-TNP) has been studied and the latter was found to have a stronger power and a longer duration than those hitherto tested including Myanesin. As appendices the analogous action of m-tolyl glycerol ether, m-ethylphenyl glycerol ether, α-naphthyl glycerol ether, and β-naphthyl glycerol ether has been studied which could not have an equal even to Myanesin.