Journal of Health Science
Online ISSN : 1347-5207
Print ISSN : 1344-9702
ISSN-L : 1344-9702
REGULAR ARTICLES
Changes in Middle Latency Auditory-Evoked Potentials of the Rat Exposed to Styrene
Yu-ping WangTakeshi SaitoToshiyuki HosokawaMasaaki KurasakiKazuo Saito
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ジャーナル フリー

2001 年 47 巻 2 号 p. 175-183

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Effects of styrene exposure on middle latency auditory-evoked potentials (MAEPs), which reflect the central auditory function, were investigated. As significant delay in latencies of No, Po, Na, and Pa components and increases in the peak to peak intervals of MAEPs, but not amplitudes, were observed in a dose-dependent manner, The present and our previous studies demonstrate that electrophysiological alterations occur before neuronal cell damage induced by styrene exposure. The present results suggested that styrene has a marked effect on the processing of auditory information related to MAEPs.
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© 2001 by The Pharmaceutical Society of Japan
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