Journal of Health Science
Online ISSN : 1347-5207
Print ISSN : 1344-9702
ISSN-L : 1344-9702
RESEARCH LETTERS
MRP5b/SMRP mRNA is Highly Expressed in Metallothionein- Deficient Mouse Liver
Toshihiro SuzukiMika AguiTadayasu TogawaAkira NaganumaKazuto NishioShinzo Tanabe
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2003 年 49 巻 6 号 p. 524-526

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To investigate whether multidrug resistance protein 5 (MRP5) functions as a xenobiotic detoxification factor, we measured MRP mRNA expression levels in metallothionein (MT)-I, II knockout mouse, and the results showed that MRP5b/SMRP, a splicing variant of MRP5, was highly expressed in the liver of MT-I, -II null mice.

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© 2003 by The Pharmaceutical Society of Japan
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