マススペクトロメトリーの裁判化学領域への応用(第2報)アヘンアルカロイドの定量

抄録

As an application of mass spectrometry to the field of forensic chemistry, the determnation of opium alkaloids was examined. Since the mass spectral data of standard alkaloid mixtures indicated that molecular ion peak heights of morphine, codeine, and nalorphine were proportional to their molar concentrations, it was possible to determine the amounts of morphine and codeine simultaneously from the ratios of molecular ion peak heights on the mass spectrum of the sample to which nalorphine was added as the internal standard. The method has been successfully used for the analysis of a sample for legal advice.