頭蓋内圧脈波の振動解析に関する研究

線形振動モデルによるシミュレーション

抄録

To understand the relation between arterial pressure (AP) waves and intracranial pressure (ICP) pulse waves, animal experiments using cats and computer simulation based on linear vibration model are carried out. In animal experiments, acute brain compression by epidural balloon inflation is performed. By increasing of ICP at the beginning of experiments, the equivalent compliance estimated by computer simulation decreases to low value. Although ICP returns to low by balloon deflation, the equivalent compliance remains low. These results suggest that the compliance estimated by the computer simulation is available for the indicator of pathological changes in intracranial functions.