Cashew nuts are widely eaten, and the juice made from them is a popular healthy drink. In this study 6- [(Z) -8-pentadecenyl] salicylic acid (1) (anacardic acid monoene) was isolated from the shell oil of Indonesian cashew nuts. From this acid, 19 derivatives were synthesized by epoxidation, methylation and/or reduction of functional groups on the aromatic ring. These derivatives were examined for their use as whitening agents which inhibit Tyrosinase activity and hyaluronidase activity, and as scarvengers of superoxide. Compounds (1 b), (4 a), (4 b), (5 a) and (5 b) derived from (1) were found to be inhibited by 7883 % in tyrosinase activity, by 9698 % in hyaluronidase activity. Scavenging activity of superoxid was 6885 %.
