論文ID: 0170095
Recent studies have suggested that a high-fructose diet leads to the development of metabolic syndrome in mammals. However, relatively little information is available regarding the absorption of fructose in the chicken intestine. We therefore investigated fructose absorption and its transporters in the chicken small intestine. The gene expression of three transporters (glucose transporter protein member 2 and 5 and sodium-dependent glucose transporter protein 1) in the jejunum of fasted chicks were lower than those in chicks fed ad libitum. The everted intestinal sacs (in vitro method for investigating intestinal absorption) showed that the concentration of fructose uptake rapidly increased within 15 min after incubation, and then gradually increased until 60 min. After 15 min of incubation, fructose uptake in the ad libitum chick intestine was approximately 2-fold that in the fasted intestine and was less than half of the glucose uptake in the ad libitum chick intestine. Our results suggest that fructose is absorbed in the small intestine of chicks and that uptake is decreased by fasting treatment with decreases in the mRNA expression of related transporters.
