抄録
TIA is a medical emergency. Because, the risk of stroke early after TIA is very high. It has been reported that immediate evaluation and management of TIA substantially reduced the risk of subsequent stroke. Therefore, TIA patients should be evaluated and treated as soon as possible in a TIA clinic during 24 hours for 365 days. Based on these backgrounds, we conducted an international multicenter cooperative, investigator-driven, web-based observational study (TIAregistry.org). Five thousand patients with TIA or minor stroke (Rankin 0 or 1) within 7 days after the onset will be recruited and followed up for 5 years. The primary endpoint is non-fatal stroke, non-fatal MI or vascular death. The secondary endpoint is any vascular event or endovascular intervention. The investigational endpoints include quality of treatments, clinical manifestations, etiologies, times from first medical attention, and risk prediction scores. The background demographics include neurological symptoms, brain MRI and MRA, carotid ultrasonography, echo cardiography, blood pressure, CBC, lipids, and glucose. More than 5,000 patients will be recruited until July, 2011. Six Japanese stroke centers join the registry to recruit the target number of 300 patients. This registry may provide important information on evaluation and management of TIA as a medical emergency.
