To evaluate the efficacy of percutaneous radiofrequency ablation (RFA) using flat-panel detector angiographic CT (FACT) for hepatocellular carcinoma (HCC), we performed RFA using FACT for 23 HCC lesions in 16 patients. After transcatheter arterial chemoembolization or infusion chemotherapy using miriplatin as a sustained-release suspension in iodized oil and/or gelatin sponge, we performed RFA. RFA needle was inserted into the target lesion under US guide. Using FACT, we could confirm whether the needle tip inserted at the target assuming enough coagulative necrosis area from all angles in all lesions. Enough ablative margins could be obtained in all lesions. No serious adverse events were observed. RFA using FACT contributed more accurate insertion for HCC. Therefore, FACT would be a more useful tool for RFA.
