A 56-year-old male patient was referred to our outpatient clinic with a chief complaint of lower right abdominal pain in 2010. He had a history of surgery for ileocecal ulcer. Colonoscopy was performed and he was diagnosed as having postoperative recurrent simple ulcer. Although mesalazine was administered, it was not sufficiently effective. Thus, salazosulfapyridine was added in 2011. Colonoscopy performed two years later showed that the ulcer had shrunk. The patient has continued to take mesalazine and salazosulfapyridine up through the present time. Five years after presentation, the ulcer at the anastomotic site was completely replaced by a scar. This combination therapy had few adverse effects and was inexpensive; therefore, it is worth attempting this therapy.
