ムタノリジンおよびグルコン酸クロルヘキシジンを家庭用口腔洗滌器で用いた場合の歯垢抑制に関する二重盲検実験について

抄録

This investigation was designed to study whether mutanolysin and chlorhexidine gluconate using a water pressure irrigating device was effective in removing or preventing formation of dental plaque. The nine subjects were devided into three groups of three subjects each according to a Latin Square design. Each subject took part in three cycles of oral prophylaxis, mouthwash assignments and accumulated plaque evaluation for a three week period.
The results of an analysis of variance showed statistically significant difference at 1 percent level between the chlorhexidine gluconate group and placebo group and at 5 percent level between the mutanolysin group and placebo group. The difference between chlorhexidine gluconate group and mutanolysin group was also significant (p<0.05). Chlorhexidine gluconate was more effective on dental plaque than mutanolysin. The plaque control effect of chlorhexidine and mutanolysin was more striking in labial surface than in any other surfaces of the teeth.