総説
創薬の標的となり得るタンパク質群に関する構造機能相関研究
2007 年 127 巻 10 号 p. 1673-1683
詳細
2007 年 127 巻 10 号 p. 1673-1683
Structural biology teaches us about the fundamental nature of biological molecules. Drug design is the most immediate medical application of structural biology. Therefore our studies have been focused on structural and functional studies of human disease-related proteins and proteins essential for the growth and development of pathogenic organisms. The present paper describes 1) structural biological studies of human autocrine motility factor, 2) structural biological studies of human ribonuclease L, and 3) structural biological studies of Plasmodium falciparum S-adenosyl- L-homocysteine hydrolase.
