Nine biopsy specimens from 3 tuberculoid (TT), 1 borderline tuberculoid (BT), 2 borderline (BB), 2 borderline lepromatous (BL), and 1 lepromatous (LL) patients were studied using immunoperoxidase procedures with monoclonal antibodies. In TT patients 4B4⁺, TCR α β ⁺, CD 4⁺ T cells were dominant in dermal granulomas. In LL patient, dermal granulomas with 4B4⁺, TCR α β⁺, CD 4⁺ T cells and 2H4⁺, TCR α β⁺, CD 4⁺ T cells also had CD 8⁺ T cells. The proportion of 4B4⁺ T cells increased in granulomas from LL to TT and 2H4⁺ T cells proportionately increased from TT to LL. TCR γ δ⁺ T cells were detected only in BB and BL patients. However, there is no difference of staining pattern of ICAM-1 or LFA-1 antigen in any type of leprosy.
These results indicate that the immunohistochemical pattern of T cells (CD 4, CD 8, 4B4, 2H4, TCR) may be useful in the diagnosis of the spectrum ofleprosy.

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After 27 years implementation of leprosy control programme, this paper gives an over all view of the current status of leprosy in Bangladesh.
In this paper the following articles are reported.
1. The country
2. The current leprosy situation (Epidemiological status)
3. National Leprosy Control Programme
4. Training Programme at National Leprosy Control Centre
5. Implementation of Multiple Drug Therapy
6. Progress of Multiple Drug Therapy activities
7. Evaluation

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In 1889 authorization for the hospital was received from Shizuoka Prefecture. For Father Testevuide spirit was life itself. His constant search for the best treatment available for Hansen's desease while providing the patients with meaning for their lives is the legacy and continuing focus of the hospital through the now 104 years of operation.

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