Necrotizing sialometaplasia is a relatively uncommon oral disorder. The lesion is often misdiagnosed as malignant based on clinical and histological findings. A 21-year-old woman visited a family dentist complaining of swelling and pain in the right hard palate. She had been aware of numbness in the right hard plate before this visit. She was transferred to our outpatient clinic for further examination. The lesion magnified at 20× showed a 15-mm swelling with ulceration of the center portion and the numbness expanded to the whole area of the right hard palate. The patient underwent an incisional biopsy and histopathological diagnosis of necrotizing sialometaplasia was made. After 8 weeks, the patient recovered from the illness without further treatment.
Angiotensin-converting enzyme (ACE) inhibitors may rarely cause angioneurotic edema of the facial and oral region. Some cases were associated with respiratory distress, and angioneurotic edema of the larynx is potentially life-threatening. We report a case of angioedema in the tongue and oral floor that was probably caused by treatment with an ACE inhibitor. The patient was an 88-year-old woman. Her chief complaint was swelling of the tongue with respiratory distress. There has been no recurrence of symptoms 1 year and 4 months after withdrawal of the ACE inhibitor.
A case of calcifying epithelioma in the submandibular region, caused by traumatic injury, is prese nted. A 56-year-old man was referred to our department about one month after bruising his right submandibular region with his stick. The lesion with subcutaneous induration was swollen and produced oppressive pain. We were confident that the lesion was a tumor, which was excised. Histopathologically, it was composed of nests or masses of shadow cells and basophilic cells. Immunohistochemical analysis showed a positive reaction in shadow cells. The histopathological diagnosis was calcifying epithelioma.
We present a case of IgA pemphigus of which the first symptom arose in the oral mucosa of a 27-year-old man, and a review of the literature. He was referred for consultation regarding a stomatitis on the lower lip. IgA autoantibodies between epidermal cells were positive and were diagnosis with IgA pemphigus (IEN type) by direct immunofluorescence of skin-biopsy specimens. Symptomatic improvement was finally achieved by long-term administration of diaphenylsulfone (DDS) and cyclosporin (CYA).
Diverticulum of the oral mucosa is reported as rare. We report three cases of diverticulum of the buccal mucosa. The three patients were middle-aged or older males, and they had no history of pain or discomfort. Clinical examination revealed diverticulum measuring 3-12mm in diameter, 5-8mm in depth posterior-interior to the papillae of Stensen's duct. Excision was carried out to deep one and no treatment were performed to sharrow cases.