1. After an injection with 5c.c. or 10c.c. of nephrotoxic serum, the amount of urine from both kidneys of rabbits remains the same as before injection.
2. After an injection with 15c.c. or 20c.c of nephrotoxic serum, the amount of urine from both kidneys of rabbits decreases, especially so in the third hour.
3. After an injection with 20cc. of spleno-toxic serum, no difference is observed practically in the amount of urine from both kidneys of rabbits.
4. After an injection with 20c.c. of normal guinea-pig serum, no difference is recognized in the smount of the urine from both kidneys of rabbits.
5. By the histological researches (Table 3-19) no alterations are recognized.
6. All cases except two (Table 5 & 6. which received an injection of 20c.c. of nephrotoxic serum) do not show albumen in the urine which is collected for three hours after injection.
The writer is indebted a great deal to Professor S. Mita for valuable suggestions and instructions in the course of this study.
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