Choroid constitutes the majority of the uvea with approximately 90% of total ocular blood flow. It supplies oxygen and nutrients to outer layers of the retina, facilitating the elimination of waste products. Additionally, choroid plays a crucial role in regulating intraocular pressure and temperature. The role of the choroid in the onset and progression of myopia has garnered attention, and evidence continues to accumulate with the development and evolution of optical coherence tomography (OCT).
Human choroid is highly sensitive to visual cues, dynamically altering its thickness bidirectionally. It plays a significant role in local growth of the eye. In myopia control therapies, significant choroidal thickening has been observed in response to interventions such as outdoor activities, orthokeratology, atropine eye drops, multifocal contact lenses, specially designed spectacles, and red light therapy. This suggests that choroidal thickness could serve as a potential biomarker for predicting future therapeutic effects.
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