Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics

Online ISSN : 1882-8272
Print ISSN : 0388-1601
ISSN-L : 0388-1601

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Issue 3-4 Pages 165-
Issue 2 Pages 59-
Issue 1 Pages 1-

Volume 4, Issue 3-4

Displaying 1-35 of 35 articles from this issue

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 165-166
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.165

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Evaluation of Efficacy of Treatment with an Absorbing Markov Chain Model

Kiichi Hirosawa

1973 Volume 4 Issue 3-4 Pages 167-173
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.167

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In general, the efficacy of any medical treatment will be evaluated from the observation of the time course of symptoms which patients will present in response to the treatment.
After employing an appropriate model of an absorbing Markov chain, these time series data can be submitted to a statistical analysis.
In the model, a patient is represented as a stochastic system. Then the time process of the reactivity of the system to the treatment is examined in terms of its transition probability.
In the present paper, the validity of the method in studying the transitional pattern of the state of patient was investigated in the case of treatment of purpura.
The method with the model above mentioned proved to be of advantage in judging statistically the efficacy of the treatment.

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Coloring of Urine by Phenothiazine Derivatives

Minoru Tsuruta, Hisashi Sato, Taiji Nakayama, Shigeru Goto

1973 Volume 4 Issue 3-4 Pages 174-178
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.174

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Patients treated with Protizinic acid, one of the phenothiazine derivatives, found that their urine turned blue when it was mixed with tap water and reported this to the doctors, being worried about the unexpected phenomena. The refore the cause of this phenomena was examined.
The color reaction of such phenothiazines as Chlorpromazine HC1 (Cp), Dimetotiazine (Dm), Protizinic acid (Pt), Promethazine HCl (Pm) and Metiazinicacid (Mt) to alkaline and acid reagents, purified water and tap water was examined. The pH of discoloring point was also determined by adding NaOH to test solutions which had been previously colored by HClO₄. It was found that Pt and Mt solutions turned blue when mixed with tap water but had no color change when mixed with purified water. This color change was especially marked with Pt. The color substance in the Pt-HClO₄ solution was not extractable by ether.
The difference between tap water and purified water in the color reaction may be attributable to residual content of chlorine and iron ions in the tap water.

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 181-183
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.181

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 184-186
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.184

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 187-190
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.187

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 191-193
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.191

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

1973 Volume 4 Issue 3-4 Pages 194-197
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.194

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[title in Japanese]

[in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 198-199
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.198

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 200-203
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.200

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Analgesic Efficacy of CL 48, 156 (Imidoline) in Patients with Episeotomy Pain

[in Japanese], S.S. Bloomfield, T.B. Barden

1973 Volume 4 Issue 3-4 Pages 204-208
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.204

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 209-211
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.209

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

1973 Volume 4 Issue 3-4 Pages 212-216
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.212

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[title in Japanese]

[in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 217-219
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.217

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 220-223
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.220

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

1973 Volume 4 Issue 3-4 Pages 224-230
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.224

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...

1973 Volume 4 Issue 3-4 Pages 231-234
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.231

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 235
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.235

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[title in Japanese]

[in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 236-237
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.236

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 238-241
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.238

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 242-244
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.242

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 245-247
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.245

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 248-250
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.248

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[title in Japanese]

1973 Volume 4 Issue 3-4 Pages 251-260
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.251

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PRINCIPLES AND PROBLEMS OF CLINICAL TRIALS ILLUSTRATED BY FINDINGS FROM THE UNIVERSITY GROUP DIABETES PROGRAM AND THE CORONARY DRUG PROJECT

Christian R. Klimt, Suketami Tominaga

1973 Volume 4 Issue 3-4 Pages 261-276
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.261

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Metabolic Studies in Man by Stable Isotope Tracer Technique

Shigeo Baba

1973 Volume 4 Issue 3-4 Pages 279-287
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.279

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[title in Japanese]

[in Japanese], [in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 288-309
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.288

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 310-317
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.310

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 318-321
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.318

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 322-324
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.322

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[title in Japanese]

[in Japanese], [in Japanese]

1973 Volume 4 Issue 3-4 Pages 325-328
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.325

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 329-331
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.329

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 332-337
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.332

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[title in Japanese]

[in Japanese]

1973 Volume 4 Issue 3-4 Pages 340-360
Published: December 30, 1973
Released on J-STAGE: June 28, 2010

DOIhttps://doi.org/10.3999/jscpt.4.340

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Erratum

1973 Volume 4 Issue 3-4 Pages 350
Published: 1973
Released on J-STAGE: July 04, 2011

DOIhttps://doi.org/10.3999/jscpt.4.3-4_350

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