The studies of the constituents of tuber aconiti (hereinafter simply called “tuber-A”) have been centered around original alkaloids like aconitine.
As the result, little attention has been paid to minute quantities of inorganic substances which are secondary consituents but evidently play the principal role in producing the mystical, medicinal effects of aconite.
This unexplored aspect has been approached by investigating, as the primary and fundamental step, the interaction between the native tuber-A (Aconitum subcuneatum Nakai) and the soil where it grows in terms of chemical constituents involved.
1. It is found that the native tuber-A and the control contain by far larger amounts of lead ion, among other matters, and cobalt ion and iron ion as well than any other commercial crude drug.
2. The interrelationship between the native tuber-A and the chemical constituents of its surrounding soil has been recognized for all substances except sodium ion. In particular, the contents of calcium ion, magnesium ion, iron ion and phosphorus ion are considerably high.
3. Irrespective of where it comes from, the native tuber-A contains more copper ion in the subordinate portion than in the main portion of its root. of all the varieties, the subordinate root of the plant produced in the region A in the Kitakami Mountains yields the largest copper ion content of 10.8mg.%, three times as much as the average value of 2.9mg.%. It seems probable, in addition, that the quantities of copper ion in the native tuber-A and in its surrounding soil are very closely related with the total amounts of alkaloids.
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