[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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　An application problem when brazing aluminium is that molten braze alloy may penetrate into the bulk. This may, for example, increase the risk for reduced corrosion resistance and may in the long run lead to coolant leakages in heat exchangers. The phenomenon is poorly understood, which motivates a closer look using synchrotron radiation based 3D imaging. Through phase-contrast tomography at the BL14-B2 beamline at SPring-8 we have recorded 3D images of aluminium sheet materials with different stages of braze alloy penetration where the braze alloy penetration process can be visualized step by step. The characteristic signs of braze alloy penetration has been identified in the 3D images and the project has provided new perspectives on the braze alloy penetration process.

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[in Japanese]

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[in Japanese]

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　Conversion to amyloid-like fibrils and/or aggregation of numerous soluble proteins is associated with several pathologies such as amyotrophic lateral sclerosis (ALS), Alzheimer’s, and Parkinson’s diseases. Cu, Zn-superoxide dismutase (SOD1) is an important anti-oxidative enzyme that protects cells. Mutations of the gene coding for SOD1 cause familial ALS. We found that the self-assembly of amyloid-like fibrils by SOD1 in certain conditions was accompanied by the formation of hydrogels rather than precipitation, notably when the concentration of the protein was sufficiently high. The structure of the hydrogels and pathogenic SOD1 fibrils remains unknown.

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