Recent developmental studies have shown that human babies learn from sensorimotor experiences starting from fetus periods. In addition, recent advance in brain imaging allows us to investigate the development of brain structures. However, how the brain functions develop is not unclear because of technical and ethical difficulties. In this study, we show a large-scale neonate cortex simulation, which consists of 2.6 million spiking neurons and 5.3 billion synaptic connections First, we determined the macroscopic anatomy of the cortex model by extracting fiber tracts and brain regions from neonate MR data. Next, we built other details of the cortex model based on experimental data. As a result of simulation, we found that our cortex simulation exhibits spontaneous activities, which are consistent with six experimental measures. Our result demonstrates that our cortex simulation possesses biological validity, suggesting that it's useful to investigate developmental mechanisms of how the brain functions.
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