Magnolamine and Related Compounds. N. An Alternative Synthesis of D (-) and L (+)-N-Methylcoclaurine.

Abstract

The optical resolution of N was carried out by means of (+)-and (-)-di-p-toluoyltartaric acid to give the compounds, Na and Nb. These compounds were converted into our objective antipodes, IIa and IIb, by hydrolysis. Absolute configuration of the above compounds was confirmed by conversion of IIa and IIb into D (-)-and L (+)-N-methylcoclaurine, respectively.