Food Science and Technology Research
Online ISSN : 1881-3984
Print ISSN : 1344-6606
ISSN-L : 1344-6606
Original papers
Addition of Whey Peptides to a Carbohydrate-electrolyte Drink Enhances its Effect on the Early Treatment of Dehydration in Rats
Kentaro ItoYuri SaitoMakoto YamaguchiKinya AshidaTaketo YamajiHiroyuki ItohToru TakahashiMunehiro Oda
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2016 Volume 22 Issue 5 Pages 623-629


Previous studies suggested that peptide absorption by peptide transporter 1 (PepT1) contributes to water absorption in the small intestine. Here, we aimed to apply this effect of peptides to a rehydration drink for the effective treatment of dehydration. We first prepared a whey peptide drink (WPD) in which the composition (whey peptides and Na+) was optimized for water absorption in the small intestine. We then evaluated the effectiveness of the WPD in an in vivo dehydration model. The results demonstrated the following: (1) the addition of whey peptides to a carbohydrate-electrolyte drink enhanced the rehydration effect in the rat dehydration model, i.e., it increased the plasma volume more quickly and more abundantly; and (2) the WPD was more effective for rehydration than a general sports drink. The WPD could be considered a new treatment option for the rapid alleviation of dehydration.

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© 2016 by Japanese Society for Food Science and Technology
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