Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Epstein-Barr Virus-positive Diffuse Large B-cell Lymphoma of the Elderly Complicated by the Onset of Acute Myeloid Leukemia
Akane KunitomiShinichi KotaniNaoya UkyoKazuo OnoHirokazu NakamineMasaharu Nohgawa
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ジャーナル オープンアクセス

2014 年 53 巻 1 号 p. 51-56

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We herein describe the case of a 62-year-old woman who presented with anemia and an 8-month history of weight loss. Bone marrow aspiration showed increased myeloblasts. The histopathology findings of biopsy specimens of the right cervical lymph node and intestinal mass indicated B-lymphoproliferative disorder (B-LPD) with Hodgkin lymphoma-like morphologic features and polymorphous diffuse large B-cell lymphoma (DLBCL), respectively. In addition, both types of lymphoma cells were positive for Epstein-Barr virus (EBV)-encoded small RNA-1. The patient was diagnosed with EBV-associated B-LPD and simultaneous acute myeloid leukemia (AML). This is the first case of a patient diagnosed with simultaneous EBV-positive DLBCL of the elderly and AML.

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© 2014 by The Japanese Society of Internal Medicine
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