Potential Cosmetic Whitening Agents from Insect Cuticle: Tyrosinase Inhibitory Activity of N-Acetyldopamine Dimers from Exuviae of Cicada, Cryptotympana tustulata FABR.

Takahiro TADA; Kazuomi OHNISHI; Kouichi SUZUKI; Hiroki TOMITA; Mariko OKAMORI; Hirotaka KATUZAKI; Takashi KOMIYA; Kunio IMAI

doi:10.5650/jos.51.355

NOTES

Potential Cosmetic Whitening Agents from Insect Cuticle: Tyrosinase Inhibitory Activity of N-Acetyldopamine Dimers from Exuviae of Cicada, Cryptotympana tustulata F_ABR.

Takahiro TADA, Kazuomi OHNISHI, Kouichi SUZUKI, Hiroki TOMITA, Mariko OKAMORI, Hirotaka KATUZAKI, Takashi KOMIYA, Kunio IMAI

著者情報

キーワード: Cryptotympana tustulata F_ABR., NADA, dimer, tyrosinase inhibitory activity, whitening

ジャーナルフリー

2002 年 51 巻 5 号 p. 355-358

DOI https://doi.org/10.5650/jos.51.355

詳細

抄録

The tyrosinase inhibitory activity of N-acetyldopamine dimers purified from the exuviae of cicada (Cryptotympana tustulata F_ABR.) was found in the present study. Isomers, trans-1, trans-2, and a mixture of cis isomers, expressed strong activity comparable to that of arbutin, a typical whitening agent. Trans-1 had the strongest activity, exceeding that of arbutin at 100 μM and was found to function quite well as a cosmetic whitening agent. The inhibition mechanism is discussed.

責任著者(Corresponding author)

J-STAGEへの登録はこちら（無料）