合成セラミドを含む人工細胞間脂質の相挙動とラメラ構造の形成機構
1994 年 43 巻 8 号 p. 656-658
詳細
1994 年 43 巻 8 号 p. 656-658
Phase behaviors and the mechanisms of the formation of the lamellar membranes for artificial intercellular stratum corneum lipids containing a synthetic pseudo-ceramide (SLE) were studied by mixing the equimole of SLE and other components of natural intercellular stratum corneum lipids (SCL) by X-ray and DSC measurements. The results showed that SCL forms a stable lamellar membrane being essentially identical to that of natural SCL. From the fact that a stable lamellar structure was obtained only in the mixed system of SLE and long-chain fatty acids, we conclude that the fatty acids play an important role as a co-operator of a self-organization of natural SCL.
