実験結核症に及ぼすクロレラ飼育の影響

抄録

For the evaluation as a nutritious foodstuff of chlorella cells containing large amounts of protein and fat, guinea pigs were fed with the diet containing the freeze-dried cells of Chlorella pyrenoidosa in place of the bran in the common diet which also included bean-curd refuse and some vegetables, and the effects of feeding on the experimental tuberculosis were investigated.
The nutritious compositions of both diets were calculated and provided as follows: the caloric ratio of common diet, protein: fat: carbohydrate=2:1:8, total calorie, 168 cal. per day to each animal; the caloric ratio of ohlorella-diet, protein: fat: carbohydrate=1.4:2:1, total calorie, 173 cal. per day to each.
After the feedings for 5 weeks with these diets, the animals were infected with 0.01mg of M. tuberculous H37Rv, and the feedings were continued for 5 weeks.
The autopsy was carried out at the sixth week after infection.
The results obtained might be briefly provided as follows:
1. It was recognized that the chlorella diet was quite useful for the animal feeding.
2. The skin reaction caused by tuberculin (x100) appeared at each third and fifth week after infection in both groups.
3. In the autopsy findings, the visceral lesions of the group fed with chlorella were less than those of the control.
4. The microscopic findings of lungs tended to be equal to the macroscopic visceral findings.
5.Colonies of tubercle bacilli developed less in the cultures of the spleen in the chlorella group than those of the control.
6.The absorption percentage of chlorella diet stood at 80%.