Chemical and Pharmaceutical Bulletin
The Pharmaceutical Society of Japan, established in 1880, is one of Japan’s oldest and most distinguished academic societies. The Society currently has around 18,000 members. It publishes three monthly scientific journals. Chemical and Pharmaceutical Bulletin (Chem. Pharm. Bull.) began publication in 1953 as Pharmaceutical Bulletin. It covers chemistry fields in the pharmaceutical and health sciences. Biological and Pharmaceutical Bulletin (Biol. Pharm. Bull.) began publication in 1978 as the Journal of Pharmacobio-Dynamics. It covers various biological topics in the pharmaceutical and health sciences. A fourth Society journal, the Journal of Health Science, was merged with Biol. Pharm. Bull. in 2012. Yakugaku Zasshi (Japanese for “Pharmaceutical Science Journal”) has the longest history, with publication beginning in 1881. Yakugaku Zasshi is published mostly in Japanese, except for some articles related to clinical pharmacy and pharmaceutical education, which are published in English.
The main aim of the Society’s journals is to advance the pharmaceutical sciences with research reports, information exchange, and high-quality discussion. The average review time for articles submitted to the journals is around one month for first decision. The complete texts of all of the Society’s journals can be freely accessed through J-STAGE. The Society’s editorial committee hopes that the content of its journals will be useful to your research, and also invites you to submit your own work to the journals.

Chairman of Committee
Ken-ichi Hosoya
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama

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27,235 registered articles
(updated on September 23, 2018)
Online ISSN : 1347-5223
Print ISSN : 0009-2363
Featured article
Volume 66 (2018) Issue 9 Pages 873-879
Manganese-Catalyzed Oxophosphorylation Reaction of Carbon–Carbon Double Bonds Using Molecular Oxygen in Air Read more
Editor’s picks

A novel aerobic manganese-catalyzed oxophoshporylation reaction of carbon–carbon double bonds of styrene derivatives and vinyl ethers using diethyl H-phosphonates was developed. This direct transformation of alkenes to b-ketophosphonates readily proceeded at room temperature via the incorporation of molecular oxygen present in air (open flask). All of the experimental procedures in this reaction can be performed in air without cooling, heating, or high pressure. This methodology serves an alternative approach to produce β-ketophosphonates because of its simplicity and mildness.

Volume 66 (2018) Issue 9 Pages 866-872
Introduction of a Polar Functional Group to the Lipid Tail of 4-epi-Jaspine B Affects Sphingosine Kinase Isoform Selectivity Read more
Editor’s picks

4-epi-Jaspine B derivatives containing a polar functional group in the lipid tail were designed and synthesized for the development of sphingosine kinase (SphK) inhibitors, which would be applicable to the treatment of autoimmune and inflammatory disorders. A biological evaluation revealed that the replacement of one methylene at the lipid tail with ether oxygen affected the inhibitory activity of 4-epi-jaspine B, leading to the identification of a selective SphK2 inhibitor.

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Journal news & Announcements
  • Chem. Pharm. Bull. Vol. 66 No. 5
    Current Topics: Natural Products Chemistry of Global Tropical and Subtropical Plants

  • Chem. Pharm. Bull. Vol. 66 No. 3
    Current Topics: Drug Discovery: Recent Progress and the Future

  • Chem. Pharm. Bull. Vol. 66 No. 2
    Current Topics: Medicinal and Bioorganic Chemistry of Nucleosides and Nucleotides

  • Chem. Pharm. Bull. Vol. 66 No. 1
    Current Topics: Recent Progress in Medicinal Chemistry