This experiment was made to see whether susceptibility to alloxan differs among different strains of mice.
Male mice of the CFW, CF1, C₃H, C₅₇BL, DDK, NC, KK, RR, SS, and AA strains of age approxi-mately 100-120 days were used. Alloxan was injected intravenously into the tail vein at a dose of 40, 60, 80 or 100mg/kg of body weight.
The results demonstrated that susceptibility to alloxan is different among the strains of mice.
The percentages of diabetics at the seventh day after injection of 40mg/kg in DDK and RR strains were 5.8% and 30.0%, respectively, while other strains did not show diabetes at this dose of alloxan.
In animals injected with 60mg/kg, the percentages of diabetics at the seventh day after injection were 25.9% in CFW, 77.2% in CF1, 90.0% in C₃H, 50.0% in C₅₇BL, 56.6% in DDK, 0 % in NC, 30.0%in KK, 50.0% in RR, 53.8% in SS, 62.5% in AA respectively.
At a dose of 80mg/kg, the incidences of diabetics at the seventh day after injection were of 100% in CF1, C₃H, SS strains, 80-90% in C₅₇BL, DDK, KK, RR and AA strains, 68% in CFW strain, and 9.0% in NC strain.
At a dose of 100mg/kg, the percentage of diabetics in NC strain was 47.8%, while 80-100% in the other strains.
The pattern of the percentage from the first day to the seventh day after injection showed different types between C₃H and NC strains. C₃H strain did not show diabetes at the first day but the percentage had been elevated since the second day in 60mg/kg, 80mg/kg and 100mg/kg groups. On the other hand, in NC strain the percentage of the second day was lower than that of the first day in 80mg/kg and 100mg/kg groups. The percentage of diabetics in other strains than C₃H and NC strains increased slowly with time after injection.

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Viable counts of various fecal bacteria were made in different strains of 4- to 5-week-old mice (Tables 2, 3, 4, 5 and 7) . The strains used were as follows: CF1, C57BL/6, DDD, C3H/He, A/Jax, BALB/c, hr/hr, KK and BDF1 (BALB/c_??_×DBA/2 _??_) bred in this institute, CF#1, C57BL/6 and ddY supplied by different breeders, and BALB/c and DBA/2 soon after imported from U.S.A. Of str.eptococci, staphylococci, lactobacilli or bacteroides, a similar count was obtained from the same strain of mice supplied by different breeders at varying seasons. On the other hand, the count of enteric bacteria, spores or yeasts was sometimes variable in each season or breeder, even about the same strain. Although some difference was observed among the mouse strains, the type of fecal flora in each strain of mice was too complicated to be classified simply.

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The report describes the outlines of the symposium held in Dun Laoghaire, Ireland in September 1965 and the activities of various institutions in Europe and U. S. A., concerning laboratory animal science and experimentation, which were visited by the three participants of the symposium. The description was made under the following titles.
The 3rd ICLA Symposium on the Husbandry of Laboratory Animals
1. Background of ICLA, 2. The 3rd ICLA Symposium (Date, place, participants, programme, summaries and review), and 3. The General Assembly of ICLA (Secretary's report, Treasurer's report, appointment of a new Governing Board and Executive Committee, discussion on future activities) .
Progress of Laboratory Animal Science and Animal Experimentation in Several European Coun-tries and U. S. A.
1. Activities of Laboratory Animals Centre and Other Organizations (England, Fed. German Republic, Poland, France and U. S. A.), 2. Production and Supply of Laboratory Animals (Conventional animals, SPF animals and gnotobiotes), and 3. Animal Experimentation.

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