IHE (Integrating the Healthcare Enterprise) has started activity in the United States in 1999. IHE laboratory domain started activity in 2002. In Japan, laboratory working group held Connectathon (interconnection test of profiles) since 2003. They gradually increased the number of participating vendors and enrich the test profiles. The latest Technical Framework includes the profile of the providing barcode labels for containers and document sharing over each facility. We show the recent activity of IHE laboratory in Japan with presenting the relation between HL7 and JLAC10 and IHE Technical Framework.

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 The target of antihypertensive therapy has been lowered gradually. Number of patients under antihypertensive therapy are increasing accordingly. Cost used for the therapy is most expensive among all medical treatments. We have verified the clinical guideline for antihypertensive therapy used in Japan. We performed cohort study to compare blood pressure levels and mortality in general population, calculated hazard rates of antihypertensive therapy in general population and odds ratio of hypertension and antihypertensive therapy between general population and patients with stroke. The total mortality and the death rate from cardiovascular disease were in lowest level until SBP/DBP of 160/100 mmHg. The death rate in persons with blood pressure more than 180/110 mmHg at the baseline and blood pressure under 160/100 mmHg at the end point was increased four times than that in the persons who had mild reduction of blood pressure (to 160-179/100-109 mmHg). The odds ratio of antihypertensive therapy was about 3.0 in patients with stroke compared with general population. Intensive blood pressure lowering may cause increase of total mortality and incidence of stroke. 160/100 mmHg is eligible for the target of the therapy to general population. Reduction of systolic blood pressure for the aged by drugs is desirable within 20 mmHg.

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 Recently, various context-aware ubiquitous clinical services based on emerging positioning solutions are coming. Especially, services based on WLAN positioning tags look potential candidates, as the services require only slight modification of existing WLAN infrastructure, a part of typical hospital information system (HIS) package. This research estimated effect of an ubiquitous asset management service on WLAN tags through business process modeling, and evaluated technical barriers for introduction through trial use of a WLAN positioning solution within existing HIS of Kyoto University Hospital. The result shows although the service may be quite fruitful for process and clinical safety improvement, conventional technology is still not fully available for daily operation in clinics. Detailed process designing considering battery life length and size of hospital must be the key factor for successful introduction.

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 The severity of symptoms and the nursing dependency score were introduced along with the medical treatment fee revision in 2004. As a result, the movement of the nursing dependency score introduction is seen in the general ward. So I have developed the system that supports the nursing dependency score evaluation needing the evaluator training. About whether the effectiveness of the evaluation support would be obtained I compared the system with the nursing dependency score check form and examined it. As a result, the evaluation omission has decreased from 17 examples to 8 as a whole. Moreover, the average of the correct answer rate rose from 84.75% to 86.90% by the system use. It is thought that there was effectiveness of the evaluation support of the system by the rise of the correct answer rate and the decrease in the evaluation omission. However, it is necessary to develop a further system to raise the correct answer rate.

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 The purposes of this research are to disclose and to generalize the actual conditions of the factors that prolong LOS (Length of Stay) with the data from several hospitals. In this research, the factors in difference in average LOS are extracted and the significant differences are inspected in order to make multiple regression analysis. As a result of the general analysis, it is found out that LOS of the patients who change the department is 15 days longer than that of the patients who don't. Moreover, as a patient gets older by one year, LOS also gets longer by about 0.1 day. As a result of multiple regression analysis classified under MDC, complications post hospitalization affects neurological disease while complications pre hospitalization does respiratory organs disease, digestive organs disease, skin disease and so on. Changing the department affects otolaryngological disease and skin disease a lot while age of patients does respiratory organs disease a lot. Therefore it is presumed that each disease is related to the difference in the incidence of complications pre hospitalization and complications post hospitalization, the difference in LOS on which complications has an in.uence, the incidence of changing the department, and the patients' age.

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