The risk of oral candidiasis is high in the elderly, but the condition is preventable by mouth rinsing. In this study,
in vitro and
in vivo experiments were conducted to ascertain the effects of mouth rinses on
Candida albicans.
The bactericidal effects of three mouth rinses, Listerine, Mondamine, and Mouthwash, on
C. albicans were investigated. Marked bactericidal effects were seen with Listerine at a final concentration of 60% and with Mondamine at a final concentration of 80%, but not with Mouthwash at a final concentration of 80%. Next, to ascertain the
in vivo bactericidal effects of Listerine on
Candida spp., nine elderly people were asked to gargle with it. The number of viable cells significantly decreased in five of the nine subjects. The strains of
C. albicans that were isolated from the three individuals whose viable cells did not decrease were completely killed by Listerine
in vitro, suggesting Listerine was not effective due to inadequate gargling.
The results of the present study suggest that the use of mouth rinses in the elderly is an effective oral care technique against
C. albicans.
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