Effects of thiourea, hydroxylamine and sodium molybdate on α-receptor activities of rat was deferens were examined in order to investigate the chemical properties of the α-receptor.
1) 20 minutes incubation of the isolated was deferens with 0.45-0.47 M thiourea solutions gaveno signifficant effects on the KCl response but caused the depression of the noradrenalineresponse and the lowering of ceiling in the dose-response curve for noradrenaline.
2) 20 minutes incubation of the was deferens with 0.5 M thiourea solution induced a considerable depression of the KCl response and a severe depression of the noradrenaline response.
3) 20 minutes incubation of the was deferens with 16 mM hydroxylamine solution caused the depression of noradrenaline response by 20-40% of the response before hydroxylamine treatment, while the KCl response was not affected signifficantly by 16 mM hydroxylamine treatment.
4) 20 minutes incubation of the was deferens with 10 mM sodium molybdate solution caused a slight increase in KCl response and nearly 20% depression in noradrenaline responses.
5) These results suggest that the α-receptor of the rat was deferens might be composed of protein. The facts that those hydroxylamine and sodium molybdate which have been known as ATPase inhibitors depressed selectively the α-receptor activity without depression of KCl response, may indicate the existence of some close relations between ATPase and α-receptor activities.

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1) Papaverine-like actions of 5 bile salts, salts, sodium cholate, desoxycholate, dehydrocholate, chenodesoxycholate and ursodesoxycholate were examined with the isolatd guinea-pig ileum and compared by their pD'₂values.
2) Hemolytic activities of above 5 bile salts were tested using rabbit red cells.
3) Desoxycholate and chenodesoxycholate showed strong papaverine-like actions, while dehydrocholate showed an extremely weak activity.
4) Bile salts caused no irreversible depression on the acetylcholine response of ileum smooth muscle.
5) Surface active agents such as saponin showed no papaverine like actions.
6) A fairly good interrelation between the hemolytic actions and the papaverine-like action of bilesalts was observed
7) It seems likely that papaverine-like actions of bile salts are unable to be ascribed to their surface active properties, but may be attributed to interactions between the bile salts and the cell membrane components of smooth muscle.

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The vagal inhibitory responses of the movements of the stomach were investigated on the anesthetized and non-anesthetized frog and bullfrog. The following results were obtained.
. The stimulation of the peripheral cut end of the vagus nerve generally produced the excitatory response of the stomach movements, but on the atropinized animals, the same stimulation which produced the exicitatory response of the stomach, produced the inhibitory response of the stomach movements.
2. The stimulation of the central cut end of the vagus, splanchnic and sciatic nerves also produced the inhibitory responses through the vagus nerve as well as the excitatory responses of the stomach. In these examples, the inhibitory response was obtained on the non-treated animals, contrary to the fact that the inhibitory responses which were obtained by the peripheral stimulation of the vagus nerve, were obtained only on the atropinized animals. This is the evidence that the inhibitory response of the stomach will occur on the physiological procedure as reflex.

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The present study was made to investigate the difference of gastric motility between hypertonic and hypo- or atonic type of stomach in healthy adults. The subjects studied were 10 adults consisting of two groups of every 5 persons with hypertonic steer horn and hypo-or atonic long stomach respectively.
Cinefluorogram of gastric motility of these subjects was taken on 16 mm cinefilm by means of an image intensifier. The size of longitudinal axis (L) and transverse diameter (T) of the gastric peristalsis was measured on each frame of the obtained film by a film motion analyzer.
In the hypertonic steer horn type the reduction of L was greater than T, and the velocity of peristalsis was fast. On the contrary the reduction of T was greater than L and the velocity of the peristalsis was slow in the case of hypo- or atonic type of the stomach.
The changes of the L and T seem to be related to the contractions of the longitudinal and circular muscle of the gastric wall respectively.
Therefore, it is conceivable that participation of the longitudinal muscle to the gastric motility is greater than that of the circular muscle in the hypertonic type, while participation of the circular muscle is greater than that of the longitudinal muscle in the hypo- or atonic type.

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