PURPOSE: Accumulation of visceral adipose tissue (VAT) is closely related to metabolic syndrome, such as
glucose intolerance, diabetes, abnormal lipid metabolism, and arterial sclerosis. In Japan, diagnosis criteria for
metabolic syndrome has been determined by the waist circumference and VAT area at the navel level (around
between Lumbar disc 4 and 5). However, a previous study demonstrated that metabolic syndrome risk in Japanese men was associated with the VAT area at 5-7cm above L4-5, not at the L4-5 level. Since an imbalance of physical activity and caloric intake are related to accumulation of the VAT, we hypothesizes that the accumulation of VAT at the different levels are related to physical activity and caloric intake. The purpose of this study was to investigate the relationship between the VAT areas at the different levels and metabolic syndrome risks in Japanese middleaged and older women.
METHODS: This study provides a cross-sectional investigation of 50 Japanese women (Obese: 32, Normal: 18).
Consecutive MRI images (from 3cm below L4-L5 to 10cm above L4-L5) were used to explore the relationship
between each VAT area and metabolic syndrome risks (total cholesterol, HDL cholesterol, triglycerides, baPWV,
fasting blood suger, HbA1c, blood pressure and number of metabolic syndrome risk factor(MetSN)).
RESULTS: Significant correlations were found between the VAT areas at the levels 8-10cm higher than L4-L5, and HDL cholesterol, fasting blood sugar and MetSN(p<0.05).
CONCLUSIONS: We found that the VAT area at the upper levels was significantly related to a metabolic syndrome risk in Japanese women.
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