Review of Polarography
Online ISSN : 1884-7692
Print ISSN : 0034-6691
ISSN-L : 0034-6691
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Volume 59, Issue 1
Displaying 1-9 of 9 articles from this issue
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Preface
Award Review Article, 2012 Shikata International Medal
  • Development of Highly-sensitive Electrochemical Biosensors
    Fumio Mizutani
    2013 Volume 59 Issue 1 Pages 5-11
    Published: May 31, 2013
    Released on J-STAGE: June 21, 2013
    DOIhttps://doi.org/10.5189/revpolarography.59.5
    JOURNAL FREE ACCESS
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    This article describes the development of biosensors with electrochemically-amplified responses. In general, chemical amplification involves a reaction sequence for a substrate to generate a relatively large amount of the product. Thus a trace concentration of analyte can be caused to yield orders of magnitude higher product concentration which may be more easily be measured than the analyte itself. For electrochemical biosensors that detect biochemical reactions on the electrode surfaces, chemical amplification procedures suitable for concentrating the electroactive species near the electrode/test solution interface should be utilized to enhance the sensor response effectively. Thus the use of combination of bio-electrochemical processes such as catalytic reaction to regenerate electroactive species and adsorptive stripping procedure to accumulate electroactive species on electrode surfaces can be useful for realizing highly-sensitive biosensors. Actually, immunoassay protocol combined with such electrochemical amplification techniques has enabled us to determine biomarkers with picomolar-levels. Recently we have successfully applied particle manipulation based on dielectrophoresis to develop rapid and separation-free immunosensing systems. The union of highly-sensitive electrochemical detection and dielectrophoretic particle manipulation (or accumulation) would provide biosensor systems suitable for the purpose of the point-of-care testing of biomarkers.
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Review Article
  • Electrochemical Analysis of Microfluidic Droplet Formation
    Mao Fukuyama, Yumi Yoshida, Jan C.T. Eijkel, Albert van den Berg, Akih ...
    2013 Volume 59 Issue 1 Pages 13-19
    Published: May 31, 2013
    Released on J-STAGE: June 21, 2013
    DOIhttps://doi.org/10.5189/revpolarography.59.13
    JOURNAL FREE ACCESS
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    This paper reports a microchemical chip for electrochemical measurement of ion transport at the water-oil interface during microdroplet formation in a microchannel. For the electrochemical measurement of the interface, the aqueous-organic-aqueous three-phase system was formed in the microchannels. The channel wall was needed to be hydrophobic in order to prevent the aqueous phases from unfavorable intrusion. By using this system, the charging current to the electrical double layer in single microdroplet was measured.
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Electrochemical Concepts
  • Theoretical Similarity between Macro- and Nano-interfaces
    Toshiyuki Osakai
    2013 Volume 59 Issue 1 Pages 21-27
    Published: May 31, 2013
    Released on J-STAGE: June 21, 2013
    DOIhttps://doi.org/10.5189/revpolarography.59.21
    JOURNAL FREE ACCESS
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    A theoretical similarity has been suggested between the surface tension (γ) of a macro-sized mercury electrode and the ion-solvent interaction energy at a nano-sized ion | solvent interface. In a previous theory (Osakai & Ebina, 1998), the ion-solvent 1:1 interaction energy was formulated as a quadratic function of the surface field strength (E) of the ion. This theory has been extended to explain a near-parabolic shape of the electrocapillary curve for a mercury electrode, i.e., the quadratic dependence of γ on the electrode potential (being roughly proportional to E at the electrode surface).
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