With the government’s increasing emphasis on arts education, the necessity of the artistic education function and brand shaping of theaters, as important carriers of urban cultural dissemination, has become more prominent. This paper takes the Guangzhou Grand Theatre as a case study to explore innovative strategies and practical paths for the branding of theatre arts education. By analyzing the basic concepts of theatre arts education and its branding, this paper examines the current advantages and challenges of theatre arts education branding, further elucidating its core value to audiences, theaters, and society. Finally, the paper proposes a four-dimensional strategy based on brand philosophy, characteristics, development, and communication. This study aims to extend theatre arts education from theaters to communities through brand operations, achieving deep dissemination from a small scale to widespread popularization, thereby providing feasible paths and prospects for developing theatre arts education branding.

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口唇裂・口蓋裂治療チームにおける授乳援助の実態および唇顎口蓋裂児の母乳育児に対する考えを明らかにすることを目的に，日本口蓋裂学会に登録されている全国の口唇裂・口蓋裂手術に携わる324の医療機関にアンケート調査を行った。その結果130施設から回答があり以下のような所見が得られた。
1．唇顎口蓋裂児の初診時の直接母乳の割合は，1割以下の施設が約50%であり，裂型に関係なく30%の施設は直接母乳の状態が把握できていなかった。
2．ほとんどの施設で授乳指導が行われ，約半数の施設は人工乳首の選択方法や専用乳首の使い方などのビン哺乳の指導だけであった。母乳栄養の指導は48%の施設が行っていた。
3．授乳困難時に勧めている乳首は72%がP型乳首で最も多く，次いでヌーク口蓋裂乳首39%，チュチュ口蓋裂用乳首34%であった。
4．口唇裂手術直後の授乳方法は35%が術前と同じ方法を行い，それ以外は傷の安静目的に細口哺食器，栄養チューブ，スプーンなどを使用していた。
5．唇顎口蓋裂児の直接母乳は82%の施設が「状況により可能」と考え，57%の施設が直接母乳の「援助が必要」と考えていた。
6．直接母乳に向けた改善策は，「出生直後からの診療チームのアドバイス」64%，「産科スタッフの授乳ケアの熟知」48%であったが，それを実施するための産院との連携システムがある施設は21%であった。また，直接母乳に向けた「口蓋床の改良」が48%であり，「専用乳首の改良」は33%であった。

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An Y-doped Σ7{4510}[0001] Al₂O₃ grain boundary was fabricated by the bicrystal method. The grain boundary segregation structure was studied using atomic-resolution scanning transmission electron microscopy and energy dispersive X-ray spectroscopy. It was found that the atomic structure of the Y-doped grain boundary differs from that of the non-doped grain boundary, indicating that Y doping induced the structural transformation from asymmetrical shape to symmetrical shape in the grain boundary core. Apart from Y, impurities of Ca were also segregated at the grain boundary. Both Y³⁺ and Ca²⁺ are segregated at the same atomic columns in the grain boundary, mainly due to their larger ionic size compared with Al³⁺. In addition, valence electron energy loss spectroscopy measurements indicate that the bandgap energy of the doped grain boundary is about 0.5 eV smaller than that of the pristine grain boundary.

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The effect of different annealing atmospheres on the atomic structures and dopant segregation behaviors in Ti-doped grain boundaries (GBs) of alumina was studied by using atomic-resolution scanning transmission electron microscopy, energy dispersive X-ray spectroscopy and electron energy loss spectroscopy. In addition to the Ti dopants, Ca impurities also segregated to the GBs. It is found that the atomic structure of Ti-doped GBs is symmetric in the reducing atmosphere, while it changes into an asymmetric one with further annealing in air. The different GB structures and segregation behaviors of Ti and Ca in air may result from the partially oxidization of Ti³⁺ to Ti⁴⁺ and less oxygen vacancies when annealed in air. Our results indicate that the annealing atmosphere strongly affect GB segregation behaviors in alumina.

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背景 : 基底細胞癌は頻度の高い皮膚癌であるが, 非露光部の外陰部の基底細胞癌はまれである. 今回, 皮膚科にて部分生検し基底細胞癌と診断され, 当院にて治療をした外陰部基底細胞癌の症例を経験したため, 細胞診所見を含め報告する.

症例 : 82 歳, 女性, 外陰部腫瘤病変を自覚し, 皮膚科でのダーモスコピーと生検により基底細胞癌と診断された. 手術のため当科受診し, 同部位より擦過細胞診を施行した. 細胞所見は炎症性細胞を背景とし, 異型細胞が集簇または重積する集塊状に出現していた. 異型細胞の集塊には, 組織所見を反映した柵状配列がみられた.

結論 : 基底細胞癌は転移することはまれで, 部分生検によって予後を悪化させる危険性はないとされている. ダーモスコピー所見や臨床所見から確定診断ができない場合, 生検により病理学的診断をすることが推奨される. 一方, 黒褐色調病変の鑑別となる悪性黒色腫は, 生検の施行において慎重な判断が必要となる. 基底細胞癌の診断において, 臨床的に強く疑われる場合には, 擦過細胞診は感度・特異度の高い検査であるとされている. 両者の鑑別のために, 臨床所見とともに擦過細胞診が安全かつ有用な診断手段である可能性が示唆された.

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Digital transformation (DX) has been regarded as a very important issue for the last few years for the industry and academia. Also, in the COVID-19 pandemic, companies have an urgent need to review the supply chain, which is the basis of DX. This is because the business environment for customers and supplies changes rapidly. Companies are looking for DX strategies, ways to proceed, and methods and tools in a chaotic world. Digital Capabilities Model (DCM) for supply networks is an effective tool to answer these needs. DCM is groundbreaking in diagnosing a company's DX maturity from a process perspective and leading to innovation, therefore attracting the attention of academicians and industry players. It is made up of six DCM Level-1 capabilities and 38 Level-2 capabilities constructed on these six Level-1 capabilities. However, there is a lack in theoretical and comprehensive reviews on practical implementation in business. This paper is one of the first academic literature reviews on DCM for supply networks. It is found that DCM is closer to a workable model than other DX maturity models because it steps into the process. By utilizing DCM, a simple and precise method for diagnosis and for discovering measures to improve the level, has been developed. Moreover, this study identifies that smart operations are an important capability in Japan.

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This study aimed to experimentally assess the sensibility of thumbnails on online video-sharing services for tourism targeting elderly people. A total of 100 males and females aged 60 and above participated in the experiment. There were 29 male participants: 1 in his 60s, 18 in their 70s, and 10 in their 80s. Of the 71 female participants, 19 were in their 60s, 43 in their 70s, and 9 in their 80s. This experiment was conducted at a welfare exchange center located in Saitama Prefecture. Four thumbnails with varying font types, font color, font sizes, and image edging were created and used in various conditions. The assessment included 11 items measuring the participants’ sensibility evaluation and 2 items measuring their comprehensive evaluation of thumbnails. Four types of experimental thumbnail conditions were prepared and randomly presented to the participants. In each condition, participants viewed thumbnails (10 seconds), answered measurement items (1 minute 30 seconds), and took a break (20 minutes). The main factors influencing sensibility evaluation were derived by conducting a factor analysis using principal axis factoring and varimax rotation on the results obtained from the experiment. Factor 1 included positive keywords such as “Enjoyable” and “Exciting.” Therefore, factor 1 was named “Curiosity.” Factor 2 included negative keywords such as “Unpleasant” and “Boring.” Therefore, factor 2 was named “Disgust.” Furthermore, in analyses using factor scores, participants’ sensitivity evaluation of thumbnails was influenced by gender. Therefore, it is important to consider gender differences when designing thumbnails based on sensitivity evaluations.

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New geometric and stereoisomeric triterpene dimers, 7, 8-dihydroisoxuxuarine Eα (2), xuxuarines Fβ (3), Gα (4) and Gβ (5), along with a known compound, scutidin αA (1), were isolated from the South American medicinal plant "xuxua" (Maytenus chuchuhuasca RAYMOND-HAMET et COLAS). Their structures were determined on the basis of spectroscopic evidence including CD spectral studies.

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Background: Achieving early rhythm control and maintaining sinus rhythm are associated with improved outcomes in patients with atrial fibrillation (AF). Pulmonary vein isolation (PVI) is a validated alternative to medical rhythm control. This study determined associations between left atrial strain reservoir (LAS_R) and AF recurrence after PVI.

Methods and Results: In all, 132 patients (88 with paroxysmal AF [PAF], 44 with persisting AF [PersAF]) who presented in sinus rhythm for de novo PVI of AF between December 2017 and January 2019 were included in the study. All patients underwent preprocedural echocardiography. After 12 months, all patients underwent 24-h Holter electrocardiogram monitoring to screen for AF recurrence. Kaplan-Meier curve analysis revealed an association between decreasing LAS_Rand increased AF recurrence, with a cut-off at 31.4%. In univariable Cox regression analysis, LAS_Rdemonstrated an association with AF recurrence, with hazard ratios (HR) of 0.83 (95% confidence interval [CI] 073–0.93; P=0.001) per 5% increase in univariable models and 0.83 (95% CI 073–0.95; P=0.005) in multivariable analysis. When clinical variables with age, sex and type of AF (PAF/PersAF) were included in the multivariable analysis, LAS_Rremained relevant in a model with age (HR 0.86; 95% CI 073–1.00; P=0.046).

Conclusions: In patients undergoing de novo PVI for AF, LAS_Rcould be of use in risk stratification regarding AF recurrence.

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Background: Radiofrequency catheter ablation (RFCA) is commonly performed in patients with non-paroxysmal atrial fibrillation (AF), but because very long-term follow-up results of RFCA are limited, we investigated the 10-year RFCA outcomes of non-paroxysmal AF.

Methods and Results: We retrospectively enrolled 100 patients (89 men, mean age 53.5±8.4years) with drug-refractory symptomatic non-paroxysmal AF who underwent 3D electroanatomic-guided RFCA. Procedural characteristics at index procedures and clinical outcomes were investigated. In the index procedures, all patients had pulmonary vein isolation, 56 (56.0%), 48 (48.0%), and 32 (32.0%) underwent additional linear, complex fractionated atrial electrogram (CFAE) and non-pulmonary vein (NPV) foci ablations, respectively. After 124.1±31.7 months, 16 (16%) patients remained in sinus rhythm after just 1 procedure (3 with antiarrhythmic drugs [AAD]) and after multiple (2.1±1.3) procedures in 53 (53.0%) patients (22 with AAD). Left atrial (LA) diameter (hazard ratio HR 1.061; 95% confidence interval (CI) 1.020 to 1.103; P=0.003), presence of NPV triggers (HR 1.634; 95% CI 1.019 to 2.623; P=0.042) and undergoing CFAE ablation (HR 2.003; 95% CI 1.262 to 3.180; P=0.003) in the index procedure were independent predictors for recurrent atrial tachyarrhythmia.

Conclusions: The 10-year outcomes of single RFCA in non-paroxysmal AF were unsatisfactory. Enlarged LA, presence of NPV triggers, and undergoing CFAE ablation in the index procedure independently predicted single-procedure recurrence. Multiple procedures are required to achieve adequate rhythm control.

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The Southwest Airlines scheduling crisis of December 2022 and its consequences have highlighted the importance of robust disruption recovery. To support advancements in schedule recovery, we present RecovAir, an Agent-Based Model that simulates the flow of aircraft, crew, and passengers in an airline’s flight network under departure and arrival rate limits and ad-hoc recovery strategies. By measuring Key Performance Indicators like On-Time Performance, cancellation count, and total delay, RecovAir quantifies simulation outcomes to support comparisons and controlled experiments with recovery parameters. We demonstrate RecovAir’s utility by synthesizing plausible scenarios for both the first day of the 2022 scheduling crisis and a day with zero cancellations in 2024 for Southwest Airlines. Using RecovAir, we simulate these scenarios while varying disruptions, recovery strategies, and a parameter that controls prioritization between delays and cancellations. Our results validate the implementation of RecovAir and show that a fast, greedy algorithm can perform nearly as well as Southwest Airlines’ actions on the first day of the scheduling crisis without initiating any ferry flights (i.e., non-revenue flights to reposition airline crew). We envision RecovAir as a platform on which researchers and airlines can evaluate recovery algorithms holistically and prepare for future disruptions.

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吸啜時の顎および舌による乳首の圧搾動作の有無と吸引圧の違いによる各種人工乳首使用時の哺乳量の差を明らかにする目的で吸啜ロボットによるシミュレーション実験を行った。その結果,以下の結論を得た。
1)吸引動作による吸引量は乳首によってかなり差があり,さらに圧搾動作が加わると特徴的な差異が認められた。
2)ビーンスターク®は吸引動作のみでは最も吸引量が少なかったが,圧搾動作が加わると吸引量は激増して最高値を示した。他の乳首は圧搾動作の有無による差はほとんどなかった。
3)吸引動作のみ,圧搾動作を伴う場合ともに吸引量の多かったのはビジョン®Mサイズ,ヌーク®S・Mサイズ,チュチュ®,ビジョン®Sサイズの順であった。
4)丸穴乳首は自然流出量が多く,クロスカット乳首では自然流出は認められなかった。

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A vacuum fusion technique was applied to determine the solubility of water in liquid oxides. Reproducibility of determined hydrogen in liquid oxides was usually ±4 to 5 ppm for samples containing. about 50 ppm hydrogen. Liquid oxides were equilibrated with the gas mixture of argon and water vapour in the range of temperature from 1500°C to 1600°C. In the lime-silica system, a minimum of water solubility was observed near the metasilicate composition. The effects of addition of P₂0₅, B₂0₃, Ge0₂, Al₂0₃ and TiO₂ respectively to the CaO-Si0₂ system (%CaO/%SiO₂=0.59) on the solubility of waterwere studied at 1500°C. The addition of acid oxides such as P₂0₅, B₂0₃ and Ge0₂ increases the solubility of water, but amphoteric oxides as Al₂0₅ and TiO₂ decrease the solubility of water. A minimum of water solubility was observed at approximately 20 moles percent of AlO_1.5 in the CaO-Si0₂-Al₂0₈ system. It was found that the effect of an addition of acid or an amphoteric oxide on the solubility of water might be closely related to the ion-oxygen attraction of cation in oxide.

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学生の「学習意欲」や「大学生活の満足度」は,どのような要因が押し上げているのか.想定される様々な要因を探るアンケートを公立S大学の学生に実施し,その結果から因子分析によって「学習意欲」「大学生活の満足度」に影響を与えていると想定される因子を抽出した.そして抽出された因子間の因果関係を共分散構造分析にて分析した結果,「教員とのコミュニケーション」は「学習意欲」を高め,さらに「大学生活の満足度」にも影響を与えていた.また,「友人とのコミュニケーション」は「大学生活の満足度」にあまり影響を与えておらず,「学習意欲」には関連がないことが示唆された.

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