2006 年 55 巻 4 号 p. 181-189
We are conducting research into the synthesis of bioactive substances that are based on monoterpenoids. As part of this research, here we synthesized a compound that introduced three kinds of pyrones (a)-(c) (which are used for flavor and are known to be problem-free from a safety aspect) into the lateral chain of four types of monoterpenoids (1)-(4), and examined which of these compounds manifest miticidal activities. The results show that, of the functional groups introduced into the lateral chain, the miticidal effect of 4-hydroxy-6-methyl-2-pyrone was especially good. Of the compounds synthesized here, it was possible to clarify that compounds (1b) and (3b) showed miticidal activity.