Journal of Oleo Science
Online ISSN : 1347-3352
Print ISSN : 1345-8957
ISSN-L : 1345-8957
Biochemistry and Biotechnology
Synthesis and Physiological Activity of Thiophenes and Furans with 3- and 4-Methoxyacetophenone Derivatives
Shinya Tachibana, Takashi Gotou, Masato Nomura
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2008 年 57 巻 2 号 p. 107-113

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The synthesis and physiological activity of thiophenes and furans with methoxyacetophenone derivatives were examined. 3-Methoxyacetophenone (1) and 4-methoxyacetophenone (2) were converted, respectively, to the oximes (3) and (4) by oximation with hydroxylamine hydrochloride, and to the primary amines (5) and (6) by reduction with LiAlH4. The primary amine derivatives were further converted into the thiophene and furan compounds (5a)∼(5h) and (6a)∼(6h), respectively. Bioassay of these compounds (5a)∼(5h) and (6a)∼(6h) on the germination of lettuce(Lactuca satiba) seeds showed that compound (5b) exhibits growthpromoting activity.
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© 2008 by Japan Oil Chemists' Society
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